DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment stet and Parl

DIOPT Version :9

Sequence 1:NP_788450.1 Gene:stet / 38169 FlyBaseID:FBgn0020248 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_001005767.1 Gene:Parl / 381038 MGIID:1277152 Length:377 Species:Mus musculus


Alignment Length:316 Identity:67/316 - (21%)
Similarity:101/316 - (31%) Gaps:117/316 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   202 ILPEERDRKYYADRY---TCCPPPFFIILVTLVELG---FFVYHSVVTGEAAPRGPIPSDSMFIY 260
            ::|...:..:|...|   |...|.||.|..|....|   .:.|.|:.:...:....|.:|.:...
Mouse    77 LIPPLEETVFYPSPYPIRTLVKPFFFTIGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSI 141

  Fly   261 RPDK----RHEI---------------------------WR------------------------ 270
            ||.|    |.||                           ||                        
Mouse   142 RPQKEGNLRKEINKWWNSLSDGQRTVTGIIAANALVFCLWRVPSLQRTMIRYFTSNPASKVLCSP 206

  Fly   271 FLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFS-GVLAG------SLGTSIFDPD 328
            .|.....|....|:..|:.|...|...:..:.|..:...:|.| ||::.      .:.|..:.|.
Mouse   207 MLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFVAVYLSAGVISNFVSYVCKVATGRYGPS 271

  Fly   329 VFLVGASGGVYALLAAHLANVLLNYHQMRYGVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSS 393
               :||||.:..:|||    |.....:.|..:| .|.:..|.            ||:.|:     
Mouse   272 ---LGASGAIMTVLAA----VCTKIPEGRLAII-FLPVFTFT------------AGNALK----- 311

  Fly   394 EFLAIDQAETAGAV------SYVAHLAGAIAG---LTIGLLVLKSFEQKLHEQLLW 440
               ||...:|||.:      .:.|||.||:.|   :|.|           || |:|
Mouse   312 ---AIIAMDTAGMILGWKFFDHAAHLGGALFGIWYITYG-----------HE-LIW 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stetNP_788450.1 EFh <75..115 CDD:298682
EF-hand_7 91..156 CDD:290234
Rhomboid 262..428 CDD:279958 48/236 (20%)
ParlNP_001005767.1 Rhomboid 207..348 CDD:279958 41/179 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0705
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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