DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stet and Rhbdl2

DIOPT Version :9

Sequence 1:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_038965543.1	Gene:	Rhbdl2 / 298512	RGDID:	1308295	Length:	302	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	114/280 - (40%)
Similarity:	172/280 - (61%)	Gaps:	31/280 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 PLFRKMVHAVAMEILPEERDRKYYADRYTCCPPPFFIILVTLVELGFFVYHSV-------VTGEA 246
            |..||:...|:..:|||. .|:.|.:|..|.|||.||:|::|.||..|:|::|       :|.:.
  Rat    39 PRGRKVHRIVSKWMLPEP-VRRTYLERANCLPPPLFIVLISLAELAVFIYYAVWKPQKQWITLDT 102

  Fly   247 APRGPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIY 311
               |.:  :|...|||:||.|.|||:.||::|||..|:..|:.:|||.|:||||||...|:..:|
  Rat   103 ---GIL--ESPLTYRPEKREEAWRFISYMLVHAGVQHIVGNLFMQLVLGIPLEMVHKGLRVGLVY 162

  Fly   312 FSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQM--RYGVIKLLHILVFVSFDF 374
            .:|||||||.:|||||...|||||||||||:..:..||::|:.:|  ..|:::||.|::.|:.|.
  Rat   163 LAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPALGIVRLLVIILIVASDM 227

  Fly   375 GFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLL 439
            |||:|.|:            |:..:    ...||:.||:||..||:::|..|...|::.|.:...
  Rat   228 GFALYRRF------------FVPAN----GSPVSFAAHIAGGFAGMSVGYTVFSCFDKTLLKDPR 276

  Fly   440 WWIALGTYLALVVFAIAFNI 459
            :||::..|:|.::||:.|||
  Rat   277 FWISIAAYVACLLFAVFFNI 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	75/167 (45%)
Rhbdl2	XP_038965543.1	Rhomboid	113..265	CDD:396315	75/167 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820