DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stet and rom-3

DIOPT Version :9

Sequence 1:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_503013.2	Gene:	rom-3 / 191000	WormBaseID:	WBGene00004402	Length:	861	Species:	Caenorhabditis elegans

Alignment Length:	272	Identity:	60/272 - (22%)
Similarity:	114/272 - (41%)	Gaps:	60/272 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 GPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSG 314
            |.||     .:..|..::|:|....:.:|||.:||..::|.|:.|....|.:.||.|:|.:||:.
Worm   572 GMIP-----FFSGDNPNQIYRLFTSLFIHAGVIHLALSMAFQMYFMAYQENLIGSKRMAILYFAS 631

  Fly   315 VLAGSLGTSIFDPDVFLVGASG---GVYALLAA---HLANVL----LNYHQMRYGVIKLL----- 364
            .::|:|.::||.|....||.|.   ||::.:..   |..::|    |.:..:.:.::.||
Worm   632 GISGNLASAIFVPYYPTVGPSSAQCGVFSSVVVELWHFRHLLDPFELKFQSIAHLIVTLLVLCIG 696

  Fly   365 --------------------HILVFVSFDFGFAIY---ARYAGDE------LQLGSSSEFLAIDQ 400
                                .|:|:...|||...|   .:|....      :|.||.|..:.|..
Worm   697 LIPWIDNWSHLFGTIFGLITSIIVYPYMDFGDKDYDPLLQYISSTVPKSPLVQRGSMSTIINIAD 761

  Fly   401 AETAGAVSYVAHL------AGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNI 459
            ..||......|:.      .|.....| ..::.|...:|.:.:..:::    :::.:||:|..:|
Worm   762 MRTAQGYGQWANAFPYRGDQGRTPVFT-AQVIWKFLRKKFNNKRSFYV----FISAIVFSILLSI 821

  Fly   460 MNGFAMFNIRVE 471
            :......|::::
Worm   822 LLVVFFGNVKID 833

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	50/215 (23%)
rom-3	NP_503013.2	Rhomboid	582..725	CDD:366759	34/142 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820