Protein Alignment stet and RHBDL3

DIOPT Version :10

• Sequence 1: NP_788450.1
• Gene: stet / 38169
• FlyBaseID: FBgn0020248
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001350764.1
• Gene: RHBDL3 / 162494
• HGNCID: 16502
• Length: 428
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 105/245 - (42%)
• Similarity: 150/245 - (61%)
• Gaps: 15/245 - (6%)

  Fly    78 EAELRRELL-RDKWKLLFDMFDPEGFGEISVEEFLEALKSPEFLSQVPMNKRELLLERAKKAKLP 141
            |||.|.... .|.||:|||.|||...|.||..:|...|:|..  |::..:|||:||..|..
Human    26 EAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHS--SKLDPHKREVLLALADS---- 84

  Fly   142 TGPGYVTFQDFVNVMSGKRTRSFKCAVHHRDREVCSENDFQLVLNEP--PLFRKMVHAVAMEILP 204
            ...|.:.:||||::||.||:.||:.|:...:|.:.|    :.:|.|.  .|.::::..||.|.||
Human    85 HADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSS----KALLEEKGLSLSQRLIRHVAYETLP 145

  Fly   205 EERDRKYYADRYTCCPPPFFIILVTLVELGFFVYHSVVTGEAAPRGPIPS--DSMFIYRPDKRHE 267
            .|.|||:|.|.|||||||:|:|.|||:|:.||:|:.|..|:...:...|.  .:..:|.|..|.:
Human   146 REIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQ 210

  Fly   268 IWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLA 317
            :||:|.|:.:|||..|||.||.:||:.|:|||||||:|||..:|.:||:|
Human   211 VWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVA 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EF-hand_7	87..157	CDD:463900	27/69 (39%)
		Rhomboid	262..428	CDD:426384	31/56 (55%)
RHBDL3	NP_001350764.1	EF-hand_7	36..100	CDD:463900	27/69 (39%)
		Rhomboid	205..>260	CDD:451297	30/54 (56%)