DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stet and rhbdf2

DIOPT Version :9

Sequence 1:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001090673.1	Gene:	rhbdf2 / 100036646	XenbaseID:	XB-GENE-966769	Length:	826	Species:	Xenopus tropicalis

Alignment Length:	209	Identity:	50/209 - (23%)
Similarity:	89/209 - (42%)	Gaps:	42/209 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 PDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFD 326
            ||:.:.:|..||   ||||.:|...:|..|:.....||.:.|..||:.||....:.|:|.:::|.
Frog   621 PDQFYRLWLSLF---LHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFL 682

  Fly   327 PDVFLVGASGGVYALLAAHLANVLLNYHQMR---YGVIKLLHILVFVSFDFGFAIYARYAGDELQ 388
            |....||.:|..:.|||.....:..::..:.   ...:|||.|::|: |.||...:
Frog   683 PYRAEVGPAGSQFGLLACLFVELFQSWQILAKPWKAFLKLLGIVLFL-FLFGLLPW--------- 737

  Fly   389 LGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLK----SFEQKLHEQLLWWIAL----G 445
                              :..:||:.|.::||.:....|.    ....|..::.:..|:|    |
Frog   738 ------------------IDNIAHIFGFLSGLLLSFSFLPYITFGTADKFRKRAMIIISLLVFVG 784

  Fly   446 TYLALVVFAIAFNI 459
            .:.:||::...:.|
Frog   785 LFASLVIWLYVYPI 798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	42/168 (25%)
rhbdf2	NP_001090673.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..78
		Rhomboid_SP	90..287	CDD:372211
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	153..180
		Rhomboid	620..761	CDD:366759	43/170 (25%)
		MFS	746..>803	CDD:391944	11/53 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920