Protein Alignment rho and RHBDL1

DIOPT Version :9

• Sequence 1: NP_001261255.1
• Gene: rho / 38168
• FlyBaseID: FBgn0004635
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: XP_024306253.1
• Gene: RHBDL1 / 9028
• HGNCID: 10007
• Length: 526
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 57/208 - (27%)
• Similarity: 90/208 - (43%)
• Gaps: 53/208 - (25%)

  Fly    24 SQEEEHATAAKETIIDIPAACSSSSNSSSYDTDCSTASSTCCTRQGEHIYMQREAIPAT-PLPES 87
            :|..|......:.::|:    .||..|||:....:..               :.|:|.. ||.|
Human   116 AQSNEQGQVCYQELVDL----ISSKRSSSFKRAIANG---------------QRALPRDGPLDE- 160

  Fly    88 EDIGLLK---------------------YVHRQ-HWPWFILVISIIEIAIF-----AYDRYTMPA 125
            ..:|:.|                     |.||. ..|.|:..:::.:|.:|     ..:::.:..
Human   161 PGLGVYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQT 225

  Fly   126 QNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIG 190
            .:     |....|.|||.|..|.:.|||.:|||:|.....||||.::||..|:|||::||..||.
Human   226 YH-----PEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRIS 285

  Fly   191 VIYMAGVFAGSLG 203
            ::|:|||.||..|
Human   286 LLYLAGVLAGEAG 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	30/60 (50%)
RHBDL1	XP_024306253.1	Rhomboid	239..>295	CDD:328780	27/55 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4469
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.880