DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho and rhbdf1a

DIOPT Version :9

Sequence 1:	NP_001261255.1	Gene:	rho / 38168	FlyBaseID:	FBgn0004635	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_005164392.1	Gene:	rhbdf1a / 798402	ZFINID:	ZDB-GENE-040704-75	Length:	893	Species:	Danio rerio

Alignment Length:	309	Identity:	66/309 - (21%)
Similarity:	111/309 - (35%)	Gaps:	104/309 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SSSSNSSSYDTDCSTASSTCC--TRQGEHI-----------YMQREAIPATPLPESEDI-GLLKY 95
            :|.::::....||:.....||  |:....|           |...||...:.:...:|: |||.:
Zfish   618 NSGNHTNLPHIDCTITGRPCCIGTKGRCEITSREYCDFMKGYFHEEATLCSQVHCMDDVCGLLPF 682

  Fly    96 VHRQHWPWFILVISIIEIAIFAYDRYTMPAQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLH 160
            ::.:                                           .||   |.:|.:..:|||
Zfish   683 LNPE-------------------------------------------VPD---QFYRLWLSLFLH 701

  Fly   161 ANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFL-----VGASGGV 220
            |...|...::..|:.....||.:.|..||.:||:.....|:|.     |.:||     ||.:|..
Zfish   702 AGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLA-----SAIFLPYRAEVGPAGSQ 761

  Fly   221 YALLAAHLANITLNY---AHMKSASTQLGSVVIFVSCDLGYALYTQYFDGSAFAKGPQVSYIAHL 282
            :.:||.....:..::   |....|.|:|..||:|:               .||...|.:...||:
Zfish   762 FGILACLFVELIQSWQILAQPWRAFTKLLCVVLFL---------------FAFGLLPWIDNFAHI 811

  Fly   283 TGALAG--LTIGFLVLKNFGHREYEQLIWWLALGVY---CAFTVFAIVF 326
            :|.::|  |:..||...:||.           |.:|   |...:|.:||
Zfish   812 SGFISGFFLSFAFLPYISFGR-----------LDMYRKRCQIIIFLVVF 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	44/162 (27%)
rhbdf1a	XP_005164392.1	Rhomboid_SP	130..347	CDD:289371
		Rhomboid	685..826	CDD:279958	43/206 (21%)
		DUF805	<792..864	CDD:294752	21/84 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820