DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho and rhbdl2

DIOPT Version :9

Sequence 1:	NP_001261255.1	Gene:	rho / 38168	FlyBaseID:	FBgn0004635	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_957498.1	Gene:	rhbdl2 / 792002	ZFINID:	ZDB-GENE-040426-732	Length:	294	Species:	Danio rerio

Alignment Length:	235	Identity:	91/235 - (38%)
Similarity:	142/235 - (60%)	Gaps:	17/235 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PWFILVISIIEIAIFAYDRYTMPAQNF---GLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANW 163
            |.||::||:.|:|:|.|.....|.:.:   |..:   .||.|.|||::|.:.|||.||||:||..
Zfish    62 PIFIILISLAELAVFIYYAVWKPQKQWITLGTGI---WDSPLTYRPEQRKEAWRFVSYMFVHAGV 123

  Fly   164 FHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHL 228
            .|:..|:::||..|||||::|....:|::||.||.||||.:|:.|....|||||||||||:..:.
Zfish   124 EHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYF 188

  Fly   229 ANITLNYAHMKSASTQLG-----SVVIFVSCDLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAG 288
            .|..:|:..|:   ..||     .:|:.|..|:|:|||.::....|   |.:||::||:.|.:||
Zfish   189 MNAIVNFREMR---VLLGVFRILVIVLIVGTDVGFALYRRFIVHEA---GLKVSFVAHIGGGIAG 247

  Fly   289 LTIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNL 328
            :|||::...|:.....:...:|:.:..|..|.:||::||:
Zfish   248 MTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	67/157 (43%)
rhbdl2	NP_957498.1	Rhomboid	104..255	CDD:279958	67/156 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107191
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820