DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rho and rhbdf1b

DIOPT Version :9

Sequence 1:	NP_001261255.1	Gene:	rho / 38168	FlyBaseID:	FBgn0004635	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_021328201.1	Gene:	rhbdf1b / 563403	ZFINID:	ZDB-GENE-130531-6	Length:	894	Species:	Danio rerio

Alignment Length:	199	Identity:	54/199 - (27%)
Similarity:	88/199 - (44%)	Gaps:	39/199 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 PDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVD 208
            ||   |.:|.:..:||||...|...::..|:.....||.:.|..||.:||:.....|:|.
Zfish   689 PD---QFYRLWLSLFLHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLA----- 745

  Fly   209 SEVFL-----VGASGGVYALLAAHLANITLNY---AHMKSASTQLGSVVIFVSCDLGYALYTQYF 265
            |.:||     ||.:|..:.:||.....:..::   |....|.|:|..||:|:
Zfish   746 SAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFTKLSCVVLFL------------- 797

  Fly   266 DGSAFAKGPQVSYIAHLTGALAG--LTIGFLVLKNFG----HREYEQLIWWLAL--GVYCAFTVF 322
              .||...|.:...||:.|.::|  |:..||...:||    :|:..|::..|.|  |::.:|.|.
Zfish   798 --FAFGLLPWIDNFAHICGFVSGFFLSFAFLPYISFGRMDMYRKRLQILVALTLFVGIFSSFVVL 860

  Fly   323 AIVF 326
            ..|:
Zfish   861 FYVY 864

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	44/162 (27%)
rhbdf1b	XP_021328201.1	Rhomboid_SP	130..348	CDD:315299
rhbdf1b	XP_021328201.1	Rhomboid	686..829	CDD:307698	44/162 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920