Protein Alignment rho and rom-1

DIOPT Version :9

• Sequence 1: NP_001261255.1
• Gene: rho / 38168
• FlyBaseID: FBgn0004635
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_498029.2
• Gene: rom-1 / 184989
• WormBaseID: WBGene00004400
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 365
• Identity: 109/365 - (29%)
• Similarity: 163/365 - (44%)
• Gaps: 88/365 - (24%)

  Fly     1 MENLTQNVNETKVDL--GQ-EKEKEASQEEEHATAAKETIIDI---------PAACSSSSNSSSY 53
            |..|...:...|:.|  || ...|||..|          ::||         .||..|:.....|
 Worm    29 MSTLASRIETRKIPLTNGQIHAIKEAPDE----------LVDIDGFQKIVTSKAAQRSTIKRIMY 83

  Fly    54 DTDCSTASSTCCTRQGEHIYMQREAIPATP-LPESEDIGLLKYVHRQHW---PWFILVISIIEIA 114
            |.                         |.| :.:|:.|.:..|:....|   |.|:|:|:||::.
 Worm    84 DM-------------------------ADPIMSDSQKIEVHSYIDSYSWCPPPIFMLLITIIQVG 123

  Fly   115 I--------------------FAYDRYTMPAQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFL 159
            |                    |.:..:|.|             .:.::.|..|.:.|||.|||||
 Worm   124 IFFFYWESDGGRSIWTDCAGCFVHHNHTAP-------------GIFIFAPKLRGEAWRFTSYMFL 175

  Fly   160 HANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALL 224
            ||...||..|::|||..||||||.|...|||.||:..|.:|||....:|....|||||.|||||:
 Worm   176 HAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAIDPNSLLVGASAGVYALI 240

  Fly   225 AAHLANITLNYAHMKSASTQLGSVVIFVSCDLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAGL 289
            .||:||:.||:..|.....::..:.:|:..|.|.|::.:::....    ..||::||:.||:.||
 Worm   241 FAHVANVILNWHEMPLRWIRVLVLFVFIFLDFGGAIHRRFYTNDC----DSVSHLAHIAGAVTGL 301

  Fly   290 TIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNLI 329
            ..|::||.|......|::|.::.|.:|.||....|:|.::
 Worm   302 FFGYVVLYNVVEHRIEKIIRYVCLFLYSAFFATTIIFVIV 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	66/152 (43%)
rom-1	NP_498029.2	Rhomboid	160..308	CDD:279958	65/151 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I2971
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5174
OMA	1	1.010	-	-		QHG29139
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	1	1.000	-	-		otm14522
orthoMCL	1	0.900	-	-		OOG6_107191
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740