DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho and rhbdl3

DIOPT Version :9

Sequence 1:	NP_001261255.1	Gene:	rho / 38168	FlyBaseID:	FBgn0004635	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_031750644.1	Gene:	rhbdl3 / 101732375	-ID:	-	Length:	350	Species:	Xenopus tropicalis

Alignment Length:	232	Identity:	100/232 - (43%)
Similarity:	148/232 - (63%)	Gaps:	8/232 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PWFILVISIIEIAIFAYDRYTMPAQNFGLPVPIP---SDSVLVYRPDRRLQVWRFFSYMFLHANW 163
            ||||:.::|:|:|.|.|  |.:....|.|....|   .::.|||.|..|:|.||:.||||:||..
Frog   104 PWFIITVTIVEVAAFVY--YGLVLDRFVLQATHPRYLRNNPLVYHPQVRVQAWRYLSYMFMHAGI 166

  Fly   164 FHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHL 228
            .|||.|:.:||..|:|||::||..||..:|:||:.||||..||.|:....||||.||||||:|||
Frog   167 EHLGVNVALQLLVGVPLEMVHGAVRISFVYIAGILAGSLAVSVADTSAPAVGASAGVYALLSAHL 231

  Fly   229 ANITLNYAHMKSASTQLGS--VVIFVSCDLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAGLTI 291
            |||.:|::.||.....|.:  .:|.:|.:.|.|::.:.:. ||:|..|..|::|||.|.|.|:|:
Frog   232 ANIVMNWSGMKCQFKLLRTAFALICMSFEFGRAVWLRLYP-SAYAPCPHPSFVAHLGGVLVGITL 295

  Fly   292 GFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNL 328
            |.:.|:|:..|..:|.:||:.|.:|..|..||:::|:
Frog   296 GVITLRNYEQRLRDQSLWWVFLAIYVLFVTFAVLWNI 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	72/154 (47%)
rhbdl3	XP_031750644.1	Rhomboid	152..301	CDD:396315	70/149 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I4466
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	1	1.000	-	-		mtm9513
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010