DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho and rhbdf1

DIOPT Version :9

Sequence 1:	NP_001261255.1	Gene:	rho / 38168	FlyBaseID:	FBgn0004635	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_004917997.1	Gene:	rhbdf1 / 100494777	XenbaseID:	XB-GENE-6083739	Length:	892	Species:	Xenopus tropicalis

Alignment Length:	199	Identity:	55/199 - (27%)
Similarity:	88/199 - (44%)	Gaps:	39/199 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 PDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVD 208
            ||   ||:|.:..:||||...|...::..|:.....||.:.|..||.:||:.....|:|     .
Frog   687 PD---QVYRLWLSLFLHAGVLHCLVSVCFQMTILRDLEKLAGWHRISIIYILSGITGNL-----T 743

  Fly   209 SEVFL-----VGASGGVYALLAAHLANITLNY---AHMKSASTQLGSVVIFVSCDLGYALYTQYF 265
            |.:||     ||.:|..:.:||.....:..::   |....|..:|.:||||        |:|
Frog   744 SAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLFAVVIF--------LFT--- 797

  Fly   266 DGSAFAKGPQVSYIAHLTGALAG--LTIGFLVLKNFG----HREYEQLIWWLAL--GVYCAFTVF 322
                |...|.:...||..|.::|  |:..||...:||    :|:..|:|.:|.:  |::....|.
Frog   798 ----FGLLPWIDNFAHFAGFVSGFFLSFAFLPYISFGKFDMYRKRCQIIIFLLIFFGLFSGLVVL 858

  Fly   323 AIVF 326
            ..|:
Frog   859 FYVY 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	46/162 (28%)
rhbdf1	XP_004917997.1	Rhomboid_SP	127..345	CDD:372211
rhbdf1	XP_004917997.1	Rhomboid	687..827	CDD:366759	46/162 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010