DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho and rhbdf2

DIOPT Version :9

Sequence 1:	NP_001261255.1	Gene:	rho / 38168	FlyBaseID:	FBgn0004635	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001090673.1	Gene:	rhbdf2 / 100036646	XenbaseID:	XB-GENE-966769	Length:	826	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	65/301 - (21%)
Similarity:	109/301 - (36%)	Gaps:	96/301 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 DCSTASSTCC----------TRQ---GEHIYMQREAIPATPLPESEDI-GLLKYVHRQHWPWFIL 106
            ||......||          ||:   ..|.|...||...:.:...::: |||.:::.::
Frog   562 DCEIKGRPCCIGTKGSCEITTREYCTFMHGYFHEEATLCSQVHCLDEVCGLLPFLNPEY------ 620

  Fly   107 VISIIEIAIFAYDRYTMPAQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIV 171
                                                 ||   |.:|.:..:||||...|...::|
Frog   621 -------------------------------------PD---QFYRLWLSLFLHAGVIHCCVSVV 645

  Fly   172 IQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFL-----VGASGGVYALLAAHLANI 231
            .|:.....||.:.|..||.:||:.....|:|.     |.:||     ||.:|..:.|||.....:
Frog   646 FQMTVLRDLEKLAGWLRISIIYILSGITGNLA-----SALFLPYRAEVGPAGSQFGLLACLFVEL 705

  Fly   232 TLNY---AHMKSASTQLGSVVIFVSCDLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAGLTIGF 293
            ..::   |....|..:|..:|:|:               ..|...|.:..|||:.|.|:||.:.|
Frog   706 FQSWQILAKPWKAFLKLLGIVLFL---------------FLFGLLPWIDNIAHIFGFLSGLLLSF 755

  Fly   294 LVLK--NFG----HREYEQLIWWLA--LGVYCAFTVFAIVF 326
            ..|.  .||    .|:...:|..|.  :|::.:..::..|:
Frog   756 SFLPYITFGTADKFRKRAMIIISLLVFVGLFASLVIWLYVY 796

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho	NP_001261255.1	Rhomboid	144..297	CDD:279958	44/160 (28%)
rhbdf2	NP_001090673.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..78
		Rhomboid_SP	90..287	CDD:372211
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	153..180
		Rhomboid	620..761	CDD:366759	45/206 (22%)
		MFS	746..>803	CDD:391944	13/51 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920