Protein Alignment SA2 and SA1

DIOPT Version :10

• Sequence 1: NP_612109.3
• Gene: SA2 / 38167
• FlyBaseID: FBgn0043865
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_477268.2
• Gene: SA1 / 33974
• FlyBaseID: FBgn0020616
• Length: 1127
• Species: Drosophila melanogaster
• Alignment Length: 1043
• Identity: 295/1043 - (28%)
• Similarity: 489/1043 - (46%)
• Gaps: 124/1043 - (11%)

  Fly    25 REECSIAPNDEPV------CVDGTVGDATNKSLLQMILSRKRLSPTNKRNSHIESVAKYWGEFYL 83
            |:|....|..|||      .:|......|:::.|..|:...:        :.|.|:...|.|.|.
  Fly    84 RKERVERPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSK--------NPIASIVDQWIEQYK 140

  Fly    84 DSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSDILSNSSSHF-SNTHIYPLI------RKPA 141
            .:...|||||:||.:..||...:|.:|...|..::.|:...:..| ..:..||||      ||
  Fly   141 ANRETALVALMQFFINASGCKGKISEDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRK-- 203

  Fly   142 DVFVNQVGSFLNALL------LVANKFRSDSYQLFLVQLTNFVMACSESNIRTFRHTATMIGLKI 200
              |.|....|:..|:      ::.::|..|:       :.:.:...|:|.:|.||||||:..:|:
  Fly   204 --FKNNFCDFVQTLVKQCQYSIIYDQFLMDN-------VISLLTGLSDSQVRAFRHTATLAAMKL 259

  Fly   201 MTILSD--------------------LKSLD---------------------DEIAMTVWMQMFN 224
            ||.|.|                    :||.|                     ||| .::...||.
  Fly   260 MTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEI-KSMLTYMFK 323

  Fly   225 SMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGSGDV-IQCSLDNISVL 288
            |:||.|.||.:.|||.:|::|:|.|...||...|..:.|:.....|:|..|:| ::| |.::..|
  Fly   324 SVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRC-LQSLLPL 387

  Fly   289 CRKDVLFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHVLSAEILTDDVCRVLEQLIMA 353
            ..||.|..::...||:|::.:|.:.|.||..::..:|:.:.....:..|||.|..|.::.:|:.:
  Fly   388 YEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYS 452

  Fly   354 ANRGLAQAAADLFILRRNGLDG---ETFCQR----------VKHLLQLFIECG-HEQADYLVDSL 404
            ::||:|||||:...:|...|..   ||..:|          |:.|:|.|||.. ||...|||||.
  Fly   453 SHRGVAQAAAEFLNVRLFHLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSF 517

  Fly   405 IDNCELVLDWKSMIAVLLENPKSRE--LSDIHCSSLIAILLAGVKQATAGEIPPGRYT------- 460
            ||:.::|.||:.|..:|||.|...|  |.:...|:||.|:::.|||:..||:|.||.:
  Fly   518 IDSNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLS 582

  Fly   461 -KDLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNEL 524
             |:||  ..|..:.:.|:.....||.||..|....:.:..||.:|:||..:.|....:.|.|..|
  Fly   583 AKELK--AIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQAL 645

  Fly   525 VEHFELIIFDQTSSTTVLQITVKTLEFLNRMIPIPLTK------QLLNSAVTNYKMAWHRTQDTS 583
            ::....::...| ...||:...||||.|........|:      .::.|||..||.|....::..
  Fly   646 LDRINQVMSMHT-GREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLI 709

  Fly   584 PSRSTHNESN--RLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDDLPPEAFSL 646
            ....|.||.:  .:..||::|::|....||:.|:|.:.|...::....:..:..  .||.||...
  Fly   710 QGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDR--CLPNEALVY 772

  Fly   647 YLKACFCCLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTC 711
            .::||:..:.|.::.:|... .:|::.|....|.:||:.::...|.|.....|..:....:...|
  Fly   773 CIEACYFSISWGLQYVENEC-ESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSIC 836

  Fly   712 DLFVLHGN-LCGSSNPSIRSVAHVPSGNELDILEGFLMEHFLELSPSDLMLETNSDQLQRIRSIL 775
            ||.::..: |..|....||.:.:....:|..||:.|:..:...|.......||..::|.:.|:.|
  Fly   837 DLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDVAQDETRIEELHKKRNFL 901

  Fly   776 TSYLKVVCLGVVPTMRASKFYEYYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKV 840
            ..|.|:|...::|||||:..::||||.:..:||:::.::..|.:.|.::||||:|.:.:.:: |.
  Fly   902 ACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVF-KS 965

  Fly   841 FPDDTRHAAGQRALRPAEFSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELAQKQPTE 905
            ..:.:......::.:  ||.:|.|||.|.|.....:.:::||.|.|:||.||.|........|..
  Fly   966 LQEQSEDGIVSKSSQ--EFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANKEPDDPVR 1028

  Fly   906 ATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDIAHLKEYRNALRPRKTKSYP 970
            |..:|.||.||..|...||.|||..|::|.:......:|:....:...|..|||:|...:|...|
  Fly  1029 APTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHGETDQAP 1093

  Fly   971 QAT 973
            .|:
  Fly  1094 VAS 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA2	NP_612109.3	IRR1	<115..>329	CDD:227824	71/268 (26%)
		STAG	132..>215	CDD:462502	31/135 (23%)
SA1	NP_477268.2	IRR1	66..>426	CDD:227824	98/362 (27%)
		STAG	190..303	CDD:462502	29/123 (24%)