Protein Alignment SA2 and Stag1

DIOPT Version :10

• Sequence 1: NP_612109.3
• Gene: SA2 / 38167
• FlyBaseID: FBgn0043865
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_001420746.1
• Gene: Stag1 / 315958
• RGDID: 1310744
• Length: 1258
• Species: Rattus norvegicus
• Alignment Length: 1003
• Identity: 238/1003 - (23%)
• Similarity: 438/1003 - (43%)
• Gaps: 156/1003 - (15%)

  Fly    69 SHIESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSDILSNSSSHF-SNTH 132
            |.::||...|.|.|......||:.|:.|.::.||....:..:.......::|:...:..| .::.
  Rat    96 SAMQSVVDDWIESYKQDRDIALLDLINFFIQCSGCRGTVRIEMFRNMQNAEIIRKMTEEFDEDSG 160

  Fly   133 IYPLI------RKPADVFVNQVGSFLNALL------LVANKFRSDSYQLFLVQLTNFVMACSESN 185
            .|||.      :|    |.:....|:..|:      ::.:::..|:       :.:.:...|:|.
  Rat   161 DYPLTMPGPQWKK----FRSNFCEFIGVLIRQCQYSIIYDEYMMDT-------VISLLTGLSDSQ 214

  Fly   186 IRTFRHTATMIGLKIMTIL-----------------------------------------SDLKS 209
            :|.||||:|:..:|:||.|                                         .:|:.
  Rat   215 VRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQE 279

  Fly   210 LDDEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGS 274
            ..|||. .:...:|..:||.|.||.:.:||.:||.|:|.|...|....|..:.|:.....|:|..
  Rat   280 NQDEIE-NMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQ 343

  Fly   275 GDV-IQCSLDNISVLCRKDVLFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHVLSAEI 338
            |:| ::| |..:..|.....||.::...|:.|::.:|.:.|.||..:|.::::.:|.....|.|.
  Rat   344 GEVRLKC-LKALQSLYTNRELFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEA 407

  Fly   339 LTDDVCRVLEQLIMAANRGLAQAAADLFILR------------------RNGLDGETFCQRVKHL 385
            |:::.|..:..|:.:|:|.:|.||.:....:                  ||..:|..    ::.|
  Rat   408 LSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNL----IRML 468

  Fly   386 LQLFIECG-HEQADYLVDSLIDNC-ELVLDWKSMIAVLLENPKSRE--LSDIHCSSLIAILLAGV 446
            :..|:|.. ||.|.||||||.::. ||:.||:.|..:|||.|...|  :||...|:||.:::..:
  Rat   469 VLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTI 533

  Fly   447 KQATAGEIPPGRYT-----KDLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKY 506
            :||.....|.||.|     ...:|:.:...:.:.|:.....||.||..|:...:.:..||::|:|
  Rat   534 RQAAEAHPPVGRGTGKRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQY 598

  Fly   507 FCFDYYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFL--------NRMIPIPLTK- 562
            |..:.|........|:.|::..:.:: ::...:.||:...||...|        ||   :.:.:
  Rat   599 FDLEIYSTGRMEKHLDALLKQIKFVV-EKHVESDVLEACSKTYSILCSEEYTIQNR---VDIARS 659

  Fly   563 QLLNSAVTNYKMAWHRTQD--TSPSRSTHNESNRLLATLRLLTVLSGHFNLSKWDLTEPLLFSLK 625
            ||::..|..:.   |..:|  .....:..::...:|:||:.||......:|:||||.......||
  Rat   660 QLIDEFVDRFN---HSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLK 721

  Fly   626 MLLRQRRLPNGDDLPPEAFSLYLKACFC---CLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYL 687
            ..:....:|.         .:.::|..|   .:.|.:..:...:.:..|:    .||...::.:|
  Rat   722 TGIEHGAMPE---------QIVVQALQCSHYSILWQLVKITDGSPSKEDL----LVLRKTVKSFL 773

  Fly   688 YVTFSLVGKSNTEPLAYPCFSYTCDLFVL--HGNLCGSSNPSIRSVAHVPSGNELDILEGFLMEH 750
            .|....:...|| |:....|...|||.::  |..:.|........|.:..:|.:.::| .|:|:|
  Rat   774 AVCQQCLSNVNT-PVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELL-SFVMDH 836

  Fly   751 -FLELSPSDLMLETNSDQ-------LQRIRSILTSYLKVVCLGVVPTMRASKFYEYYVKYHAPFG 807
             |::....:..:|.:.:.       |.:.|::|.::.|::...:|....|:..:::|:||:..:|
  Rat   837 VFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYG 901

  Fly   808 DVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRHAAGQRALRPAEFSELMELANRLAKI 872
            |:::.::....|.:.|..|.|:    :|...::|.:..:..........|..|.:.|||.|.|..
  Rat   902 DIIKETLSKTRQIDKIQCAKTL----ILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALT 962

  Fly   873 LISNPMEHRECVIALHRSGILFVFELA-QKQPTEATKKLPFLRVLKVFVPLLLVQDKTRILNFFE 936
            ...:.::.||.|..||:.||.|.|:.. ||........|.||.||..|...||.|||..:.::.|
  Rat   963 FGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLE 1027

  Fly   937 PY--EQLIIPTCNRNDI-AHLKEYRNAL 961
            .:  ||::.   .|.|: ..|..|||:|
  Rat  1028 KFLTEQMME---RREDVWLPLISYRNSL 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA2	NP_612109.3	IRR1	<115..>329	CDD:227824	58/268 (22%)
		STAG	132..>215	CDD:462502	23/135 (17%)
Stag1	NP_001420746.1	IRR1	105..>398	CDD:227824	67/305 (22%)
		STAG	160..273	CDD:462502	20/123 (16%)