Protein Alignment SA-2 and Stag2

DIOPT Version :9

• Sequence 1: NP_612109.3
• Gene: SA-2 / 38167
• FlyBaseID: FBgn0043865
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: XP_006257565.1
• Gene: Stag2 / 313304
• RGDID: 1562042
• Length: 1268
• Species: Rattus norvegicus
• Alignment Length: 1093
• Identity: 272/1093 - (24%)
• Similarity: 469/1093 - (42%)
• Gaps: 184/1093 - (16%)

  Fly     3 DISFDDAVLNDSQA--SNQMDFEIREECSIAPNDEPVCVDGTVGDA-TNKSLLQMILSRKRLSPT 64
            :|..|..:|.:|:.  |:..|||..|..:........|..|..|.| ..||...   ..|..|..
  Rat     6 EIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKSGNG---GGKPPSGP 67

  Fly    65 NKRNSH---------------------IESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIP 108
            |:.|.|                     ::||...|.|.|......||:.|:.|.::.||....:.
  Rat    68 NRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVT 132

  Fly   109 DDTSMPFSYSDILSNSSSHF-SNTHIYPLI------RKPADVFVNQVGSFLNALLLVANKFRSDS 166
            .:.......|:|:...:..| .::..|||.      :|....|...:|      :||.....|..
  Rat   133 AEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG------VLVRQCQYSII 191

  Fly   167 YQLFLVQ-LTNFVMACSESNIRTFRHTATMIGLKIMTIL-------------------------- 204
            |..:::. :.:.:...|:|.:|.||||:|:..:|:||.|
  Rat   192 YDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMI 256

  Fly   205 ---------------SDLKSLDDEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYP 254
                           .:|:...|||. .:...:|..:||.|.||.:.:||.:||.|:|.|...|.
  Rat   257 GKRANERLELLLQKRKELQENQDEIE-NMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYS 320

  Fly   255 HCHLQPTSLRIFYEALNDGSGDV-IQCSLDNISVLCRKDVLFSEIVALTSEFREILVELCLGKED 318
            ...|..:.|:.....::|..|:| ::| |..:..|.....|.|::...||.|::.:|.:.|.||.
  Rat   321 DAFLNDSYLKYVGWTMHDKQGEVRLKC-LTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEY 384

  Fly   319 AIAEKSVQFLTHFHVLSAEILTDDVCRVLEQLIMAANRGLAQAAAD-----LF---------ILR 369
            .:|.::::.||.....|.|:||.:.|..:..|:.:|:|.:|.||.:     ||         |::
  Rat   385 DVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGIMK 449

  Fly   370 RNGLDGETFCQRVKHLLQLFIECG-HEQADYLVDSLIDNC--ELVLDWKSMIAVLLENPKSRE-- 429
            |.|..|.. ...||.|:..|:|.. ||.|.|||||:.| |  ||:.||:.|.::|||.|.|.|
  Rat   450 RRGRQGPN-ANLVKTLVFFFLESELHEHAAYLVDSMWD-CATELLKDWECMNSLLLEEPLSGEEA 512

  Fly   430 LSDIHCSSLIAILLAGVKQATAGEIPPGRYT-------KDLKREPRQGAQERATKCLAPVLPELL 487
            |:|...|:||.|:|..::||.....|.||.|       |:.|.:  ...:.|.|:..|..||:||
  Rat   513 LTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKTQ--LDDRTRITELFAVALPQLL 575

  Fly   488 RTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFL 552
            ..|:...:.:..||:||:||..:.|........|:.|:.....|: ::.:.|.||:...||...|
  Rat   576 AKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIV-EKHTDTDVLEACSKTYHAL 639

  Fly   553 --------NRMIPIPLTK-QLLNSAVTNYKMAWHRTQD--TSPSRSTHNESNRLLATLRLLTVLS 606
                    ||   :.::: ||::.....:.   ...:|  ........:::.::|:||:.:|...
  Rat   640 CNEEFTIFNR---VDISRSQLIDELADKFN---RLLEDFLQEGEEPDEDDAYQVLSTLKRITAFH 698

  Fly   607 GHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDDLPPEAFSLYLKACFCCLCWDMENLEGTALNNVD 671
            ...:|||||     ||:....|.:..:.|| |:|.:.....|:.....:.|.:..:..:.....|
  Rat   699 NAHDLSKWD-----LFACNYKLLKTGIENG-DMPEQIVIHALQCAHYVILWQLAKITESTSTKED 757

  Fly   672 -------MDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTCDLFVLHGN-LCGSSNPSI 728
                   |..:|.:..|      |:|     ..|| .:....|:..||:.::..: :.......:
  Rat   758 LLRLKKQMRVFCQICQH------YLT-----NVNT-TVKEQAFTILCDILMIFSHQIMSGGRDML 810

  Fly   729 RSVAHVPSGNELDILEGFLMEH-FLE----LSPSDLMLETNSDQLQRI---RSILTSYLKVVCLG 785
            ..:.:.|..:....|..|:::| |:|    .:.:|...|..:.:::.:   |::|.::.|::...
  Rat   811 EPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYT 875

  Fly   786 VVPTMRASKFYEYYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRHAAG 850
            ||....|:..::.|:||:..:||:::.:|....|.:.|..|.|::.:...|:.::..::     |
  Rat   876 VVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEN-----G 935

  Fly   851 QRALRPAE-FSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELAQKQPTEATKKLP--- 911
            ....|.:. ||.:.|||.|.|.....:.::.||.:..||:.||.|.|    |:|....:..|
  Rat   936 YNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAF----KEPNPQGESHPPLN 996

  Fly   912 --FLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDI-AHLKEYRNAL 961
              ||.:|..|...||.|||..:..:.|.:....: :..|.|: ..|..|||:|
  Rat   997 LAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQM-SLRREDVWLPLMSYRNSL 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA-2	NP_612109.3	STAG	134..217	CDD:285686	26/130 (20%)
Stag2	XP_006257565.1	STAG	157..265	CDD:400698	22/113 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353512
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5537
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60131
OrthoDB	1	1.010	-	-		D167826at2759
OrthoFinder	1	1.000	-	-		FOG0000572
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11199
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.860