Protein Alignment SA2 and stag3

DIOPT Version :10

• Sequence 1: NP_612109.3
• Gene: SA2 / 38167
• FlyBaseID: FBgn0043865
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: XP_012808812.2
• Gene: stag3 / 100145469
• XenbaseID: XB-GENE-995439
• Length: 1253
• Species: Xenopus tropicalis
• Alignment Length: 1093
• Identity: 250/1093 - (22%)
• Similarity: 431/1093 - (39%)
• Gaps: 226/1093 - (20%)

  Fly    12 NDSQASNQMDFEIREECSIAPN----------------DEPVCVDGTVGDATNKSLLQMI-LSRK 59
            ::|.:....|||  |..|..|.                :|.||.         |.|.:.| :.|.
 Frog    75 DESISDEGSDFE--ETLSKRPRRASPGETVAAKRPRIAEETVCA---------KDLFEAIRMGRS 128

  Fly    60 RLSPTNKRNSHIESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSDILSNS 124
            .:        |:  :...|.:.|.....|||:.|:.|::...|.:..:..:.......|||:...
 Frog   129 AM--------HV--LVDDWLDSYKQDREAALLELINFLMLACGCNGVVTLEMLENMQNSDIIRKM 183

  Fly   125 SSHFS-NTHIYPLI--RKPADVFVNQVGSFLNALLLVANKFRSDSY--QLFLVQLTNFVMACSES 184
            :..|: .|..|||:  .||...|....|.|...|:   |:.:.:..  :|.:..|.:.:...|:|
 Frog   184 TMEFNEETPDYPLLLSTKPWKKFHANFGDFFKVLV---NRCQYNIIYDELLMDALISLLTGLSDS 245

  Fly   185 NIRTFRHTATMIGLKIMT--------------------------------------ILSDLKSLD 211
            .:|.||||:|...:|:|:                                      :|:..:.|.
 Frog   246 QVRAFRHTSTFAAVKLMSGLVKVAWDVSHHLNTTKRQFVVEHAKSPETRSPERLEALLAKQRGLQ 310

  Fly   212 DEIAMTVWMQ--MFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGS 274
            ..:...|.|.  :|..:||.|..|...|||.:|:.|:|.|...|....|..:.|:.....|.|..
 Frog   311 GNLEEVVDMMNGIFKGVFVHRYCDTSADIRAICMEEIGVWMRTYSQSFLSDSCLKYVGWTLYDKQ 375

  Fly   275 GDV-IQC-----SLDNISVLCRKDVLFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHV 333
            |.| :||     ||.::..:..|..||      ||.|:..:|.:.|.||..:|.::::.:.....
 Frog   376 GAVRLQCIRTLHSLYSVPEMAPKLELF------TSRFKNRMVFMVLDKEQQVAVEAIKLIGLISQ 434

  Fly   334 LSAEILTDDVCRVLEQLIMAANRGLAQAAADLFILR-------------RNGLDGETFCQRVKHL 385
            ...::|:...|..:...:..::|.::.||......|             ||.|...:|   .:.|
 Frog   435 NMEDMLSKKDCDTIYPFVFVSSRAVSSAAGAFLYQRVLAHTVAETSPKGRNRLGNVSF---FRLL 496

  Fly   386 LQLFIECG-HEQADYLVDSLIDNCELVL-DWKSMIAVLLENPKSRELSDIHCSSLIAILLAGVKQ 448
            :..||:.. .|.|.||||||.:.....| ||.....:||...:.  |.|...|:||.||:|.::|
 Frog   497 MSFFIKSKLPEHAAYLVDSLWECAGAPLQDWVCQTDLLLLEEEG--LDDTDESALIEILVASMRQ 559

  Fly   449 ATAGEIPPGRY-------TKDLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKY 506
            |..|..|.||.       .||.|.|.:    .|.|:.:...||.||..::...:.:..||::..:
 Frog   560 AVEGTSPVGRVPARRAFALKDRKAEDK----SRLTRHMILALPPLLAKFSADSKKVRTLLKITSF 620

  Fly   507 -----FCFDYYHE--QNRMGQLNELVE-HFELIIFDQTSSTTVL-----QITVKTLEFLNRMIPI 558
                 :|.|...:  ...:.::.|::| |.|..:.:..|....:     |...:..:.....:..
 Frog   621 MELEIYCTDRMEKFLDTLLAEVQEILEKHTEEDVLESCSRALYILCDRKQALYQRADIARSTLMD 685

  Fly   559 PLTKQLLNSAVTNYKMAWHRTQDTSPSR-STHNESNRLLATLRLLTVL-SGHFNLSKWDLTEPLL 621
            .||.:.|....       ...|:|.|.. :.:|    :.||::.::.| ||| :||.|:|..|
 Frog   686 RLTGRFLQQVP-------EIMQETEPDEDAVYN----IAATMKRISPLYSGH-DLSHWELFGP-- 736

  Fly   622 FSLKMLLRQRRLPNGDDLPPEAFSLYLKACFCCLCWDM---ENLEGTALNNVD-----MDEYCDV 678
             ..::||  :.:..| ::|.:.....|..|...|.|::   .|.:|.. |.:.     :.::||:
 Frog   737 -CSQILL--KGMDTG-EVPEQIVMAALTCCHFSLLWELFHISNSKGPQ-NQISPLKQKLRQFCDI 796

  Fly   679 LHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTCDLFVLHGN-LCGSSNPSIRSVAHVPSGNELDI 742
            ....|.|.            ...:....|....||.|:.|: :.......::.:|:.||.:....
 Frog   797 CQGCLSDL------------NAAIRKQAFVLLSDLLVIFGSPIAQEQRFYLQPLAYRPSLSLQAE 849

  Fly   743 LEGFLMEHFLELSPSDLMLETNSDQLQRIRSILTSYLKVVCLGVVPTMRASKFYEYYVKYHAPFG 807
            |.|||:::.. ..|.:......::.|...|::|..|.|::....:....||..:.:|||::|.:|
 Frog   850 LAGFLLDNVF-TDPEEENEARRTETLHERRNLLAGYCKLILYSSLQLHSASDIFRHYVKFNASYG 913

  Fly   808 DVMRCSMELALQRNPIHFAMTMLHTC------------LLLYAKVFPD--DTRHAAGQRALRPAE 858
            |:::                ..||.|            ||...:.|.:  ....:..||:.||
 Frog   914 DLIK----------------ETLHKCRSISREETTKTVLLSLTQAFTELCQEGDSPPQRSSRP-- 960

  Fly   859 FSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELAQKQPTEATKKLPFLRVLKVFVPLL 923
            |.|:..||.|||.:...:...:|:.::.||:.||.:... ..|....:.:.|.||.||..|....
 Frog   961 FLEIRGLARRLALLYGPDQRRYRQDIVLLHKEGIKYCLR-ENKTSDWSPQNLLFLDVLSEFSHKT 1024

  Fly   924 LVQDKTRILNFFEPYEQLIIPT--CNRNDI-AHLKEYRNAL-----RPRKTKS 968
            :.:||..:|.:.|...:..:|:  ...|:| |....||.:|     .|..|:|
 Frog  1025 IKEDKKALLRYLEETTERCLPSQPVKDNEIWAPFLAYRKSLCADEESPPSTES 1077

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA2	NP_612109.3	IRR1	<115..>329	CDD:227824	65/264 (25%)
		STAG	132..>215	CDD:462502	24/124 (19%)
stag3	XP_012808812.2	IRR1	29..>428	CDD:227824	88/382 (23%)
		STAG	192..305	CDD:462502	23/115 (20%)