DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FucTD and FUT4

DIOPT Version :9

Sequence 1:	NP_612107.1	Gene:	FucTD / 38164	FlyBaseID:	FBgn0035217	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_002024.1	Gene:	FUT4 / 2526	HGNCID:	4015	Length:	530	Species:	Homo sapiens

Alignment Length:	351	Identity:	86/351 - (24%)
Similarity:	133/351 - (37%)	Gaps:	91/351 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 ILLWNEP-----SLVNAPAHVEC-------GCLVTTSRSHNDKA-------FDAVVISADHPYSF 174
            :|||.||     |....|.  :|       ||.:.|.|:...:|       .|.|....|.|..:
Human   191 VLLWWEPFGGRDSAPRPPP--DCRLRFNISGCRLLTDRASYGEAQAVLFHHRDLVKGPPDWPPPW 253

  Fly   175 EGLGGVKLHP---------DFYAVYAAKKPL--SSTQNP-----LTNFTLPP------------F 211
                |::.|.         |:....||.:.|  ||.:.|     ..||..|.            |
Human   254 ----GIQAHTAEEVDLRVLDYEEAAAAAEALATSSPRPPGQRWVWMNFESPSHSPGLRSLASNLF 314

  Fly   212 NLTMTYRLDSQLIWTDYYFSHTNLARRLKWFRAPSKSFADDMPATTVLRLESEILKKSRLAVYLV 276
            |.|::||.||. ::..|.:.:             .:|...|.|:    .|...:.:|..|..::|
Human   315 NWTLSYRADSD-VFVPYGYLY-------------PRSHPGDPPS----GLAPPLSRKQGLVAWVV 361

  Fly   277 YEVNEKTLPESLYMEELRKYADLDAHD-----------NCLGTDDCSHYHFMLIFETSACPDYVP 330
            ...:|:. ....|..:|.::..:|...           ..|.|  .:.|.|.|.||.|...||:.
Human   362 SHWDERQ-ARVRYYHQLSQHVTVDVFGRGGPGQPVPEIGLLHT--VARYKFYLAFENSQHLDYIT 423

  Fly   331 PQM-SMAMDKLLVPVLIG--GGNLTNLVPSHSYISSQDFATPQDLIIHLKDLANNQLEYRRYFWW 392
            .:: ..|:....|||::|  ..|....||..::|...||.:...|..:|..|..|...|||||.|
Human   424 EKLWRNALLAGAVPVVLGPDRANYERFVPRGAFIHVDDFPSASSLASYLLFLDRNPAVYRRYFHW 488

  Fly   393 HSIYRLRKTS---QPYCALCSLIQQS 415
            ...|.:..||   :|:|.:|..:|::
Human   489 RRSYAVHITSFWDEPWCRVCQAVQRA 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FucTD	NP_612107.1	Glyco_tran_10_N	125..228	CDD:293644	36/145 (25%)
FucTD	NP_612107.1	Glyco_transf_10	268..427	CDD:279224	45/165 (27%)
FUT4	NP_002024.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..112
		Glyco_tran_10_N	186..331	CDD:293644	36/146 (25%)
		Glyco_transf_10	353..525	CDD:279224	45/165 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2619
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D394490at33208
OrthoFinder	1	1.000	-	-		FOG0000215
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11929
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850