DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9168 and CG15695

DIOPT Version :9

Sequence 1:	NP_612106.2	Gene:	CG9168 / 38163	FlyBaseID:	FBgn0035216	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster

Alignment Length:	616	Identity:	210/616 - (34%)
Similarity:	331/616 - (53%)	Gaps:	53/616 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KKFYVDSPSCKMPEMDPFSADIMRFFKRRQFRECSSDKDLLISEFDSHLRQYRIKIDENSAQQHL 102
            ||::|.||.|:|...:||:.:|...:|:..:..|...:|::...::.....||:..:|||.
  Fly   154 KKYFVHSPQCQMSHPNPFANNIQHIYKKHSYIVCDKSRDMITVNYNVTDSTYRLHKNENST---- 214

  Fly   103 KKFGNATLKCEYQVIGRNKKDSFPDNHFSFSKLQPLSQSFLVPKTIDFISTQCHAVHGNIDLKLL 167
                     |.::.|.|....:..|:.:.........|.||||..:..:.|.|.....:   |:.
  Fly   215 ---------CCFKQILRAGTSANADHKYKLGPCVEFHQDFLVPTEVSAMITYCRRPPFD---KVS 267

  Fly   168 QKDAFLFVQDRLNH-EHKNTEHHRPDLQSKPNVIILGIDSTSRMNLRRSMPKVHKFLQRPGWFEM 231
            |||||.||..|.:. |:..|.|.|     :|:|::.||||.|||||..:||:::::|....|||:
  Fly   268 QKDAFSFVHPRKDQIENPTTPHRR-----RPSVLLWGIDSISRMNLELTMPRMYEYLNNQHWFEL 327

  Fly   232 QGYNKVGENTLPNLLAILTGNAEENALFNGRFGHSGF-------IDKLKFIWQLFKKNGYMTAFG 289
            |||||:|:||.|||:|:|||       ||..:.::..       :|...|||:.||..||.|||.
  Fly   328 QGYNKMGDNTFPNLMAVLTG-------FNKTYANARCHPEKVRGLDACPFIWKDFKDKGYTTAFA 385

  Fly   290 EDCAKINTFNYQKPGFKQQPVDFYLRNFIVALETILKTRREFGNVFCLGRKLGFQYVFDFARQFM 354
            ||.:|.:||:|...||...|.|.|.|..::|:|..|...:.....:|||||...:|::|...||.
  Fly   386 EDWSKFSTFDYSSRGFFNPPTDVYGRPLVLAVEKELTILQRGQMPYCLGRKPASEYIYDMGVQFT 450

  Fly   355 QRFENSAPVFGIFWSNSFTHEDFLGATALDHVFLEYLTLYDELGFFNRSIVMVLSDHGYRYGVTR 419
            ....||. .||:||:|:|:|.||...:|:|...::|:...|:.|..:.:|::..||||.|:|..|
  Fly   451 MVNRNST-FFGMFWTNTFSHNDFSMPSAMDERMVKYMRTLDKNGIMDNTIIIFFSDHGSRFGPLR 514

  Fly   420 QASKSGYLEERLPLMFIHVPPWFRKIYPQYVENLKINQNRLSSGFDLHMTLHHLLHLNATSMADF 484
            ... ||::|||||.::|.||.|.|:.||:.:.||::|:|||:|.:|:|.||.|:|.|:...  |.
  Fly   515 NLD-SGFVEERLPFIYIRVPRWIREKYPKLLRNLQMNKNRLTSPYDIHATLRHILELDTPK--DK 576

  Fly   485 SPKLQASQCKMCQSLFFQLPANRNCSHAGIREKWCSCEP-TETVTNQRLLRKVAQEVVHHMNRHL 548
            .|:  ...|..|.|:|.::..:||||.|||.:.||:|.. ::..|.....|.::.::|..:|.::
  Fly   577 LPR--PDGCSSCHSVFEEVDWSRNCSQAGIEDHWCACNSFSDVPTTDPSARSMSTQLVEAINEYV 639

  Fly   549 RDRNLTTLCQNYALKKVLYLDSKISLSEDSVEDEQLHTYIITFETNPSSAHFEATVQWNSEKETL 613
            ..:..|..|....|.::    |.:....:|      :.|:|.....|..|.|||||.|::..:.:
  Fly   640 ASKKGTKRCSRLKLNRI----SSVQRRGNS------NRYLIQLMAQPGDALFEATVDWDASAQRI 694

  Fly   614 NMNVDELSRLESYEKHSKCTRDPIIKKYCIC 644
            ...:..:|||::|...|:|:.....||||||
  Fly   695 PAQMPSISRLDTYAAKSRCSSVKETKKYCIC 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9168	NP_612106.2	DUF229	64..566	CDD:308570	176/510 (35%)
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	176/509 (35%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	120/286 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469412
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27040
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	1	1.000	-	-		mtm4742
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.960