DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9168 and CG32984

DIOPT Version :9

Sequence 1:	NP_612106.2	Gene:	CG9168 / 38163	FlyBaseID:	FBgn0035216	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_788014.2	Gene:	CG32984 / 34218	FlyBaseID:	FBgn0052984	Length:	650	Species:	Drosophila melanogaster

Alignment Length:	651	Identity:	250/651 - (38%)
Similarity:	376/651 - (57%)	Gaps:	42/651 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLC-SIQFLLCKAKLSLHSHYPNVAKTL---EN-KKFYVDSPSCKMPEMDPFSADIMRFFKRRQF 68
            :|| .|.|||...|::  |:..|...|:   || |:|||:|.:|:|..::||:|:..:.:..:.|
  Fly    17 ILCIFILFLLIVWKIT--SYGVNDVLTIKYNENQKRFYVNSSNCQMAYVEPFNAEFTKLYTPKNF 79

  Fly    69 RECSSDKDLLISEFDSHLRQYRIKIDE----NSAQQHLKKFGNATLKCEYQVIGRNKKDSFPDNH 129
            ..||:..||:...|||.|:||.:.:||    ..:|....||.     |.||.|...:.   .|::
  Fly    80 TRCSNQSDLVTVHFDSILKQYVLHVDEEVLHKLSQSKSNKFA-----CFYQNITYGQS---ADHY 136

  Fly   130 FSFSKLQPLSQSFLVPKTIDFISTQCHAVHGNIDLKLLQKDAFLFVQDRLNHEHKNTEHHRPDLQ 194
            ....|....:..::||..:..:..:|.:  |: :.::||:|||.|||      ::.|..:. |:.
  Fly   137 DRMGKKTKFTHDYVVPLNVQGMLVECRS--GD-EKRILQEDAFSFVQ------YQKTSPNL-DID 191

  Fly   195 SKPNVIILGIDSTSRMNLRRSMPKVHKFLQRPGWFEMQGYNKVGENTLPNLLAILTG---NAEEN 256
            .|.:||:.|||:.||.||||.||.|..||:.|||:||.|||||.:||.||:.:||||   |:.:|
  Fly   192 RKASVIMYGIDTVSRTNLRRLMPVVFGFLKSPGWYEMMGYNKVADNTYPNIFSILTGYSPNSAKN 256

  Fly   257 ALFNGRFGHSGFIDKLKFIWQLFKKNGYMTAFGEDCAKINTFNYQKPGFKQQPVDFYLRNFIVAL 321
            .:.:..  ..|.:||:.|||:..|||||:||:.||....|.|||.||||..:|.|:|.|..:.||
  Fly   257 QICDTT--QPGCLDKIPFIWKDMKKNGYLTAYAEDTVFSNIFNYMKPGFLSRPTDYYFRPLLDAL 319

  Fly   322 --ETILKTRREFGNVFCLGRKLGFQYVFDFARQFMQRFENSAPVFGIFWSNSFTHEDFLGATALD 384
              |||.........|:||||:|...|:||:.||||||:....|::|.||||..:|:||...:|:.
  Fly   320 EKETIKLYCPGCKMVYCLGRRLANSYIFDYCRQFMQRYVADRPIWGFFWSNHISHDDFSMLSAMQ 384

  Fly   385 HVFLEYLTLYDELGFFNRSIVMVLSDHGYRYGVTRQASKSGYLEERLPLMFIHVPPWFRKIYPQY 449
            |..:..|..:::.|.|..:|::..||||.|:|...:..:| :||||.|:|||::|||||:.||:|
  Fly   385 HKIVGDLLNFEKDGSFEHTIMIFFSDHGSRFGPLMRTRES-FLEERQPIMFIYLPPWFREKYPRY 448

  Fly   450 VENLKINQNRLSSGFDLHMTLHHLLHLNATSMADFSPKLQASQCKMCQSLFFQLPANRNCSHAGI 514
            ||.|..|||||||.||::.||.|::::...    ......:..|..|||||::||.:|:||.|.|
  Fly   449 VEALAQNQNRLSSNFDIYNTLKHIINIEGL----VEDTKWSYDCPQCQSLFYELPESRSCSEAAI 509

  Fly   515 REKWCSCEPTETVTNQRLLRKVAQEVVHHMNRHLRDRNLTTLCQNYALKKVLYLDSKISLSEDSV 579
            .|.:|:|...|.|.......::|:.||..:|:.|:..||..||.:..||.|...:.:|:.|::.|
  Fly   510 PEAYCTCHNYEEVQEDHGTWRMAELVVDRINQFLQYHNLQNLCSSLTLKLVNITEVRITESDEHV 574

  Fly   580 E-DEQLHTYIITFETNPSSAHFEATVQWNSEKETLNMNVDELSRLESYEKHSKCTRDPIIKKYCI 643
            . .:.|..|...|:.:.:.|.|.|||.::.:.|.|.:||:.:||:..|...:.|..|.|.|.:||
  Fly   575 SLGKGLRHYHTKFQVHQNLAEFFATVLYDRKTEELQINVELISRINIYRPDASCLDDNIQKLFCI 639

  Fly   644 C 644
            |
  Fly   640 C 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9168	NP_612106.2	DUF229	64..566	CDD:308570	202/510 (40%)
CG32984	NP_788014.2	DUF229	75..561	CDD:308570	202/510 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469431
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27040
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960