DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG9168 and CG9525

DIOPT Version :9

Sequence 1:NP_612106.2 Gene:CG9168 / 38163 FlyBaseID:FBgn0035216 Length:648 Species:Drosophila melanogaster
Sequence 2:NP_609260.1 Gene:CG9525 / 34217 FlyBaseID:FBgn0032080 Length:678 Species:Drosophila melanogaster


Alignment Length:703 Identity:202/703 - (28%)
Similarity:328/703 - (46%) Gaps:132/703 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSLGRNVFLLCSIQFLLCKAKLS----------LHSHY--------PNVAKTLENKKFYVDSPSC 47
            |...:.:..:.:| ||:....||          .|.||        |.:.|.|||:|..:     
  Fly     1 MKTSKTLIFIIAI-FLISHLSLSKKRNSQFNQVQHEHYIKTSECHIPYINKPLENEKGNI----- 59

  Fly    48 KMPEMDPFSADIMRFFKRRQFRECSSDKDLLISEFDSHLRQYRIKIDENSAQQHL----KKFGNA 108
                             ::|...||.|:.|:...||....||.:.::::.||..|    ||..|.
  Fly    60 -----------------KKQHTICSKDESLINLRFDEKSHQYLLYVNDHVAQLKLRSMKKKSPNL 107

  Fly   109 T-LKCEYQVIGRNKKDSFPD-----------------NHFSFSKLQPLS--QSFLVPKTIDFIST 153
            . ..|.|:.:.|..:|...|                 :.|.:|..:.:.  ..::||.:::.:..
  Fly   108 IGYNCSYRELKRLNRDYIVDAPVVYVCYLTDRSLKFEDQFLYSLGEEVKFWNGYIVPPSVEGMRA 172

  Fly   154 QCHAVHGNIDLKLLQKDAFLFVQDRLNHEHKNTEHHRPDLQSKPNVIILGIDSTSRMNLRRSMPK 218
            .|.    |...:.||.|.|:.||....:....:.|.      .|||:::|.|..|::|.||:.|.
  Fly   173 TCR----NELAEDLQSDTFVLVQPPKTYAPLISWHR------IPNVLLIGFDGISQINFRRNFPL 227

  Fly   219 VHKFLQRPGWFEMQGYNKVGENTLPNLLAILTGNAEENALFNGRFGHS--GFIDKLKFIWQLFKK 281
            |...|:...||.|.||..:||||..||:|.|||.: .:.|.|.:...|  |.:..:..||:.|||
  Fly   228 VFNQLKMQDWFRMDGYTGIGENTQSNLMASLTGYS-PHTLMNLKCDSSVIGCLKTVPLIWKHFKK 291

  Fly   282 NGYMTAFGEDCAKINTFNYQKPGFKQQPVDFYLRNFIVALETILKTRREFGNVFCLGRKLGFQYV 346
            .|::||:||..:  |.|:.:|.|..:..:|||.|:         |..:.     |:.|:...::.
  Fly   292 KGFITAYGEGIS--NLFDSEKYGIFEGTIDFYARH---------KNLQS-----CIDRRFNIKHN 340

  Fly   347 FDFARQFMQRFEN-SAPVFGIFWSNSFTHEDFLGATALDHVFLEYLTLYDELGFFNRSIVMVLSD 410
            :|:..:|::|..| :.|.||:|:.|..|:..:..| .:....|:.:..:.::|...:|||::.| 
  Fly   341 YDYCEEFLKRHANTNRPFFGVFFGNGITNRSYDNA-RIQTELLDKVKKFKKMGILTQSIVVLFS- 403

  Fly   411 HGYRYGVTR-QASKSGYLEERLPLMFIHVPPWFRKIYPQYVENLKINQNRLSSGFDLHMTLHHLL 474
                |.|:. :..|:.:.:|.||:::|.:||||:...|:.|:.|:||..||:|.:|||:||.|||
  Fly   404 ----YPVSSVKEKKTNFSQEDLPILYIWLPPWFKAFRPEIVQALRINSKRLTSPYDLHLTLQHLL 464

  Fly   475 HLN------ATSMADFSPKLQASQCKMCQSLFFQLPANRNCSHAGIREKWCSCEPTETV-TNQRL 532
            .|.      ...:.|         |..||:||..:|.||.||.|||.|..|.|:..:.: :||..
  Fly   465 ELGERWPRAVDKLVD---------CPTCQTLFAPVPENRTCSDAGIGESQCPCDSYKLLSSNQMK 520

  Fly   533 LRKVAQEVVHHMNRHLRDRNLTTLCQNYALKKVLYL----DSKISLSEDSVEDEQLHTYIITFET 593
            ...|.:::|..:|..|...||..||.|..||.|..:    |.|:|...         ||...|..
  Fly   521 QLSVGKQIVRSINEFLNHHNLHELCHNLTLKSVKMVLQRKDRKLSSGS---------TYRAYFSA 576

  Fly   594 NPSSAHFEATVQW-NSEKETLNMNVDELSRLESYEKHSKCTRDPIIKKYCICK 645
            ||::|.|..|::: |:.:|...:||:.::||.:|:..|.|.|....:|:||||
  Fly   577 NPNNAEFSTTIRYANNRQELEYINVESINRLNNYQNDSSCMRRLRGRKFCICK 629

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9168NP_612106.2 DUF229 64..566 CDD:308570 160/536 (30%)
CG9525NP_609260.1 DUF229 66..554 CDD:281053 159/529 (30%)
ALP_like 206..466 CDD:293745 96/282 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45469441
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D31599at6960
OrthoFinder 1 1.000 - - FOG0005924
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10974
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
54.950

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