DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9168 and F15H10.7

DIOPT Version :9

Sequence 1:	NP_612106.2	Gene:	CG9168 / 38163	FlyBaseID:	FBgn0035216	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_505674.1	Gene:	F15H10.7 / 184555	WormBaseID:	WBGene00008874	Length:	666	Species:	Caenorhabditis elegans

Alignment Length:	692	Identity:	181/692 - (26%)
Similarity:	302/692 - (43%)	Gaps:	114/692 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFLLC-SIQFLLCKAK--LSLHSHYPNVAKTLENKKFYVDSPSCKMPEMDPFSADIMRFFKRRQF 68
            :|::| .:.:.|.:.:  .|.|.|:..:.|..:::    ....|.:|:.||:...|:.::.:...
Worm    23 IFVICFGVYYGLFRTETDFSTHPHFLYLQKLRDSQ----SKSECVIPDADPWDPSILSYYSKPSP 83

  Fly    69 RECSSDKDLLISEFDSHLRQYRIKIDENSAQQHLKKFGNATLKCEYQVI--------GRNKKDSF 125
            ..||:                       ...|.:|.|.|..|..|.|||        |....::.
Worm    84 LVCST-----------------------MQVQAVKSFNNGILTFEPQVIKNARCYKTGIRHDENV 125

  Fly   126 PDNHFSFSKLQPLSQSFLVPKTIDFISTQCHAVHGNIDLKLLQKDAFLF-----VQDRLNHEHKN 185
            .|....:.|..||:   |...:...||.:...:....| .||:.:.|.:     |....|.::|.
Worm   126 TDLDVIYEKPVPLN---LTHTSSIKISDEVFQITCESD-NLLKSEIFKYHYTQIVPKSSNIKNKV 186

  Fly   186 TEHHRPDLQSKPNVIILGIDSTSRMNLRRSMPKVHKFLQRPGWFEMQGYNKVGENTLPNLLAILT 250
            .|....|.   |:||::|:||.||.|..|.|.|.:|:::..|:.:|:|:.|:.:||..|||||||
Worm   187 IEQSTSDF---PSVIMIGLDSMSRGNFVRQMQKTYKYMKEAGFIDMEGHMKIHDNTYGNLLAILT 248

  Fly   251 G----NAEENALFNGRFGHSGFIDKLKFIWQLFKKNGYMTAFGEDCAKINTFNYQK--PGFKQQP 309
            |    ..:|.:.......|..| |:..|||:.|..|||.|.|.||...|.||.|:.  .||.:||
Worm   249 GKRGVGVKEFSTEINESWHIAF-DEFDFIWKTFSDNGYATLFAEDRPDIGTFTYKNMLEGFLKQP 312

  Fly   310 VDFYLRNFIVALETILKTRREFGNVF--CLGRKLGFQYVFDFARQFMQRFENSAPVFGIFWSNSF 372
            .|.|:|.|.::....|.:||...:.:  ....|:..:|:    .:|:::::.... |..:||..
Worm   313 TDHYIRPFWISAFWSLISRRSVASCYDSTPQHKIQLKYL----EEFLEKYDKKRK-FAFWWSQD- 371

  Fly   373 THEDFLGATALDHVFLEYLTLYD---ELGFFNR------SIVMVLSDHGYRYGVTRQASKSGYLE 428
                      :.|.||..:...|   |..|.|.      ||::|.||||:||...|: :..|.:|
Worm   372 ----------MSHGFLNLIGKVDDDFEKFFKNNEKRMEDSIIIVFSDHGHRYDKIRE-TVIGRIE 425

  Fly   429 ERLPLMFIHVPPWFRKIYPQYVENLKINQNRLSSGFDLHMTLHHLLHLNATSMADFSPKLQASQC 493
            .|:|...|.:|...:|.|||.||||.:|...:::.||::.:|..:    ||...  ..|...:..
Worm   426 SRMPFHSIRIPDGIKKKYPQIVENLMVNSKLMTTQFDVNDSLRKI----ATGKV--GEKWTQTDR 484

  Fly   494 KMCQSLFFQLPANRNCSHAGIREKWCSCEPTETVTNQRLLRKVAQEVVHHMNRHLRDRNLTT--- 555
            |...|.|...|....|..|||...:|.|. :|....:...::.|.|::..:|..|.:...|.
Worm   485 KRSYSYFDPFPKRIGCYEAGIPSDFCPCF-SEIEIPKSEAKEAAVELMRIVNDLLENTEKTEEYE 548

  Fly   556 ---------LCQNYALKKVLYLDSKISL--------SEDS-VEDEQLHTYIITFETNPSSAHFEA 602
                     :|....::.|.:...::.:        |||: ::...|..:::.....||:|..|:
Worm   549 PDSKELTEYMCTPMEIQNVEFSSVRLPMLSVLKDVKSEDTPLQSFSLQYHVVVRAKAPSNALLES 613

  Fly   603 TVQWNSEKETLNMNVDELSRLESYEKHSKCTRDPIIKKYCIC 644
            |::.|.:..|.: ::.|:.|...|...|.|..|.|:||.|.|
Worm   614 TLEHNLKTNTWS-SLGEVERNNKYGNTSFCVNDRILKKICHC 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9168	NP_612106.2	DUF229	64..566	CDD:308570	146/543 (27%)
F15H10.7	NP_505674.1	DUF229	79..568	CDD:281053	146/543 (27%)
F15H10.7	NP_505674.1	ALP_like	195..472	CDD:293745	98/298 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4742
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910