DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment 312 and K12H4.2

DIOPT Version :9

Sequence 1:	NP_001261254.1	Gene:	312 / 38161	FlyBaseID:	FBgn0029514	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_498757.2	Gene:	K12H4.2 / 176135	WormBaseID:	WBGene00019677	Length:	190	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	57/224 - (25%)
Similarity:	90/224 - (40%)	Gaps:	49/224 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLTRVFRLVHDRRLSVPVLRCFHHEFSKPPQQAAKGQEIEGNPEKTLVAGVQDKYKIFRDEEATE 65
            ||||..||       .|:|:.         :..|:...||            ::|  |.:.|.|.
Worm     1 MLTRFTRL-------RPILQL---------RYLAQNSHIE------------EEY--FEELEPTG 35

  Fly    66 IFDVEEARHQEQQLPEPDLELDHYYGLNLKRGVRGVFD-VEDLVELLRKENVDDIFVCYVPE-NL 128
            |.    :.|:..|.|.   :...:...||....    | ||::|..|..:...|:||....| .:
Worm    36 II----SSHETSQEPP---KRTGFRSQNLSEDA----DFVENVVGALTDQRAKDVFVVKSEETEM 89

  Fly   129 KYVDHLVVCSGRSYRHMLSTAEFVRRMFKIKRGKGDIL--PRIEGDKSRDWMAMDLGNIALHIFS 191
            ....|.::||..:.|...:.:|.:|.:.||.......:  .|....:|..|...::..:.:|:.|
Worm    90 TPYTHKIICSAFNSRQASAISENLRSLLKIDGVSNGSMSHARRSTKRSNGWYVSEVERVQVHVMS 154

  Fly   192 PSAREEYDLESLWA----IGSEFDRESQK 216
            ...||:||||::||    |..|.|.|.||
Worm   155 EECREKYDLEAIWAGDDRILDEIDEEKQK 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
312	NP_001261254.1	RsfS	105..204	CDD:280555	26/101 (26%)
K12H4.2	NP_498757.2	RsfS	65..167	CDD:280555	26/101 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I8209
eggNOG	1	0.900	-	-		E1_COG0799
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1590818at2759
OrthoFinder	1	1.000	-	-		FOG0005796
OrthoInspector	1	1.000	-	-		oto18655
orthoMCL	1	0.900	-	-		OOG6_101813
Panther	1	1.100	-	-	LDO	PTHR21043
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7333
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.810