Protein Alignment Ptp61F and PTPRR

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_002840.2
• Gene: PTPRR / 5801
• HGNCID: 9680
• Length: 657
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 89/287 - (31%)
• Similarity: 146/287 - (50%)
• Gaps: 21/287 - (7%)

  Fly    13 AAARLQIEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRI 77
            :|:|:...::.:|.....|....|..|........|:.   :..||..:  |||:.:.|...||:
Human   373 SASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEI---DIPRHGTK--NRYKTILPNPLSRV 432

  Fly    78 VLKRGSV-----DYINANLVQ-LERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEK 136
            .|:..:|     .|||||.:: ....|:.:|.||||:::||..||.|||::.|..::|:.||.||
Human   433 CLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEK 497

  Fly   137 KQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTW 201
            .: ||.||||.:.|.       :.|:.|.::.:....|:..|  .|...:...::.|..:.||:|
Human   498 NE-KCVLYWPEKRGI-------YGKVEVLVISVNECDNYTIR--NLVLKQGSHTQHVKHYWYTSW 552

  Fly   202 PDFGIPSSPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVS 266
            ||...|.|....|:.:..|.:....|:..||.||||||||||:|.|.........:.:.|..:..
Human   553 PDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDAL 617

  Fly   267 KVLCELRSYRMGLIQTADQLDFSYQAI 293
            .::|:||..|.|::||::|.:|.:.|:
Human   618 SIVCQLRMDRGGMVQTSEQYEFVHHAL 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	79/233 (34%)
PTPRR	NP_002840.2	R-PTPc-R	417..642	CDD:350459	79/236 (33%)