Protein Alignment Ptp61F and PTPRN2

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001295197.1
• Gene: PTPRN2 / 5799
• HGNCID: 9677
• Length: 1038
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 104/293 - (35%)
• Similarity: 153/293 - (52%)
• Gaps: 29/293 - (9%)

  Fly    19 IEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLK--- 80
            :|...|:|    :|..||....|..:|:..  |:..::|..|...||...|..|||||::||
Human   758 MEDHLKNK----NRLEKEWEALCAYQAEPN--SSFVAQREENVPKNRSLAVLTYDHSRVLLKAEN 816

  Fly    81 -RGSVDYINAN-LVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHL 143
             ....|||||: ::..:.....||.|||||..||..||.||||.....::||..|.|....:|:.
Human   817 SHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYH 881

  Fly   144 YWPNEMGADKALKLPHVKLTVELVRLETY-QNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIP 207
            |||     |:...|.|: ..|.||....: ::|:.|.|.|.:|:|.::|.|.|||:.:|.|.|:|
Human   882 YWP-----DEGSNLYHI-YEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVP 940

  Fly   208 SSPNAFLKFLQQV----RDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYG-ECNVSK 267
            ||..:.|.|.::|    |...|      |.:||||.|.|||||:.|:|..|..:.|.. |.:::.
Human   941 SSSRSLLDFRRKVNKCYRGRSC------PIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAA 999

  Fly   268 VLCELRSYRMGLIQTADQLDFSYQAIIEGIKKL 300
            .|..||..|.|::||.:|.:|:..|:.|.:..:
Human  1000 TLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAI 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	91/238 (38%)
PTPRN2	NP_001295197.1	RESP18	98..>152	CDD:464394
		Receptor_IA-2	532..620	CDD:463293
		R-PTP-N2	750..1032	CDD:350458	104/291 (36%)