Protein Alignment Ptp61F and ptpn22

DIOPT Version :9

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001092890.1
• Gene: ptpn22 / 565606
• ZFINID: ZDB-GENE-060503-458
• Length: 887
• Species: Danio rerio
• Alignment Length: 654
• Identity: 143/654 - (21%)
• Similarity: 243/654 - (37%)
• Gaps: 225/654 - (34%)

  Fly    47 EKQFSTSESERHTNRGLNRYRDVNPYDHSRIVL----KRGSVDYINANLVQLERAERQYILTQGP 107
            |:.:.|:.:::..|...|||:|:.|:||||:.|    .:...|||||:.::.....:.||.||||
Zfish    46 ERTYPTTAADKQDNVKKNRYKDIVPFDHSRVKLSLFTSKNDTDYINASFIKGVSGSKAYIATQGP 110

  Fly   108 LVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETY 172
            |.:||..||.|:||...:.::|:.:..|..:.||..|||...|.....:    ..|:.....|..
Zfish   111 LSNTVLDFWRMIWEYNIQVIVMVCREFEMGRKKCERYWPESKGDVFVCE----AFTILYESDENK 171

  Fly   173 QNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVR---DSGCLSRDVGPAV 234
            .:::.|..|:|  ..|:||.:.|.||..|||.|:|.|..|.|:.||::|   |:     :..|..
Zfish   172 GDYLTRTLKVT--FKQESRRLKQLHYVNWPDHGVPDSIPAILELLQEMRIYQDN-----EEIPIC 229

  Fly   235 VHCSAGIGRSGTFCLVDCCLVLIDKY---GECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEG 296
            :|||||.||:|..|.:|....|:.:.   .:.::.:::..:|:.|..::||.:|    |:.:...
Zfish   230 IHCSAGCGRTGALCAIDYTWNLLKRQIIPEDFSIFELVKGMRTQRPSVVQTKEQ----YELVYRT 290

  Fly   297 IKKLHDPTFLDAEEP-----------LISNDTE-------------THTLDELPPPLPPRVQSLN 337
            ||.|.:......|.|           ::|:.:|             .|..||:      ||...|
Zfish   291 IKLLFERYLAALEAPSNKVPDSSSPAMLSSGSELSDISDFSDQEQTEHRNDEI------RVDEYN 349

  Fly   338 LPLAPNSGG------------ILSLNMRAAQANGA-----------ESIGKELSKD--------- 370
             .:..||..            ::|..:..|..:.|           .||...|..|
Zfish   350 -HVMQNSASWQQPHSQTFSPEVMSNKLTPADLHNARCEWVQITDQSSSIAPVLQTDFTTCGSQKP 413

  Fly   371 -------------ALNNFI----NQ--------HDMI---------------------------- 382
                         :.:|::    ||        |:.:
Zfish   414 EASTSLSTTSTQVSCSNYLEWVENQEASPVVKDHNTVIPSTLCLTVEDPYFGPESPPGSNNPSVL 478

  Fly   383 ------------------------------HDAE-------VADSRPLPPLPVRAFNDSDSDEDY 410
                                          ||:.       .:|....||||.|      :.|.:
Zfish   479 NCTAHEIWTEKPCFTIPSLALNNQALEMPKHDSNNKGGNTLSSDEESPPPLPER------TPESF 537

  Fly   411 LLDDDDEDDTDEDEEYETINEHDADPVNGHVPATTQPHADDVNANNEKPAVPVDEQHKANGIDPI 475
            ::.|:....:: :|:.||     ::.:...:|.:|.  ::.||.:|....||           |:
Zfish   538 IMADETSGQSN-NEKSET-----SELLTLVIPTSTS--SESVNRDNPPSPVP-----------PL 583

  Fly   476 PGQLPAS-----------------PENELKR-RKRNEYQASLEQKVNDMKRKQRENEDKQLAAKK 522
            |.:.|.|                 |:..:.| .|..|:.....:...||||....::    :.|.
Zfish   584 PERTPESFEMAMDADLVQNVTQEKPQEVVMRVGKSLEWSGQTNEGQTDMKRSWSRSK----SLKL 644

  Fly   523 RRSL 526
            |.||
Zfish   645 RMSL 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	81/257 (32%)
		PTPc	62..295	CDD:238006	78/242 (32%)
ptpn22	NP_001092890.1	Y_phosphatase	59..291	CDD:278528	79/246 (32%)
		PTPc	61..291	CDD:238006	78/244 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000