DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp61F and ptpn9b

DIOPT Version :9

Sequence 1:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_690659.5	Gene:	ptpn9b / 562170	ZFINID:	ZDB-GENE-090313-52	Length:	754	Species:	Danio rerio

Alignment Length:	325	Identity:	113/325 - (34%)
Similarity:	164/325 - (50%)	Gaps:	49/325 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KDKGPQWHRFYKEICETCDREAKEKQFSTSE-SERHTNRGLNRYRDVNPYDHSRIVL------KR 81
            |.||  .::.|:||       .||....|.: |::.:|:..|||.||...|.||:.|      ..
Zfish   455 KKKG--IYQEYEEI-------RKEPPAGTFDYSKKASNQIKNRYSDVLCLDQSRVHLCPLNDEDD 510

  Fly    82 GSVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWP 146
            .:.|||||:.:...:....||.|||||..|.|.||.|||||....::|..:::|:.::||..|||
Zfish   511 ETSDYINASFMDGYKWSNAYIATQGPLPKTFGDFWRMVWEQMVLIIVMTTRVVERGRVKCGQYWP 575

  Fly   147 NEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPN 211
            .|.|..:    .:....|..|.:|.:|:|.....:|.:.:|.:.|||..:.|.:|||||:|.|.:
Zfish   576 LEAGRTE----EYGYFLVRNVHIEVFQDFKLSHLELFNTQTGECREVSHYLYMSWPDFGVPKSAS 636

  Fly   212 AFLKFLQQV--RDSGCLSRDV----------GPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECN 264
            |.|.|...|  |....| |.:          .|.||||||||||:||||.:|.||..::..|..:
Zfish   637 AMLDFRAHVKHRQESSL-RTLYPDWTGPPGGPPVVVHCSAGIGRTGTFCTLDICLSRLEDIGTVD 700

  Fly   265 VSKVLCELRSYRMGLIQTADQLDFSYQAIIE-----GIKKLHDPTFLDAEEPLISNDTETHTLDE 324
            :.:.:..:|:.|...|||.||..|.|:|:||     |:.           :|:..:|||..|..|
Zfish   701 IKQTVRRMRTQRAFSIQTWDQYYFCYKAVIEYGQQSGLL-----------QPVEWSDTELETDSE 754

Fly 325 324
Zfish 755 754

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	101/279 (36%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	93/250 (37%)
ptpn9b	XP_690659.5	CRAL_TRIO_N	9..57	CDD:215024
		SEC14	79..229	CDD:214706
		PTPc	458..731	CDD:214550	102/286 (36%)
		PTPc	486..731	CDD:238006	93/249 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000704
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.870