Protein Alignment Ptp61F and Lar

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001260594.1
• Gene: Lar / 35259
• FlyBaseID: FBgn0000464
• Length: 2032
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 104/291 - (35%)
• Similarity: 149/291 - (51%)
• Gaps: 37/291 - (12%)

  Fly    48 KQFSTSESERHTNRGLNRYRDVNPYDHSRIVLK--RGSV--DYINANLVQLERAERQYILTQGPL 108
            :||:...|....|:..|||.:|..|||||:.|.  .|.|  ||||||.....|....|:.|||||
  Fly  1488 QQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPL 1552

  Fly   109 VDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETYQ 173
            .:|...||.|.||.|:..::|:.:|.|:.:|||..|||.. |.:     .:.::.|.:...:...
  Fly  1553 QETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTR-GTE-----TYGQIFVTITETQELA 1611

  Fly   174 NFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVRDSGCLSRDVGPAVVHCS 238
            .:..|.|:|........||:.|..:|.|||.|:|..|..||:||::.|  .....:.||.:||||
  Fly  1612 TYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCR--ALTPPESGPVIVHCS 1674

  Fly   239 AGIGRSGTFCLVDCCL------VLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEGI 297
            ||:||:|.:.::|..|      .:||.||.     |.| ||:.|..::||.||..|.:.||:|.|
  Fly  1675 AGVGRTGCYIVIDSMLERMKHEKIIDIYGH-----VTC-LRAQRNYMVQTEDQYIFIHDAILEAI 1733

  Fly   298 ---------KKLHDPTFLDAEEPLISNDTET 319
                     :.||  |.|  ::.||:...||
  Fly  1734 ICGVTEVPARNLH--THL--QKLLITEPGET 1760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	88/237 (37%)
Lar	NP_001260594.1	I-set	36..129	CDD:400151
		Ig strand B	53..57	CDD:409353
		Ig strand C	66..70	CDD:409353
		Ig strand E	93..97	CDD:409353
		Ig strand F	108..113	CDD:409353
		Ig strand G	122..125	CDD:409353
		Ig	141..228	CDD:472250
		Ig strand B	157..161	CDD:409353
		Ig strand C	170..174	CDD:409353
		Ig strand E	192..196	CDD:409353
		Ig strand F	206..211	CDD:409353
		Ig strand G	218..221	CDD:409353
		IgI_3_RPTP_IIa_LAR_like	237..319	CDD:409401
		Ig strand A	237..239	CDD:409401
		Ig strand A'	244..248	CDD:409401
		Ig strand B	251..259	CDD:409401
		Ig strand C	264..270	CDD:409401
		Ig strand C'	272..274	CDD:409401
		Ig strand D	277..281	CDD:409401
		Ig strand E	286..291	CDD:409401
		Ig strand F	298..305	CDD:409401
		Ig strand G	309..318	CDD:409401
		FN3	322..411	CDD:238020
		FN3	<382..747	CDD:442628
		FN3	712..810	CDD:238020
		FN3	832..898	CDD:214495
		FN3	<867..1269	CDD:442628
		fn3	914..998	CDD:394996
		R-PTPc-LAR-1	1498..1735	CDD:350401	93/250 (37%)
		R-PTP-LAR-2	1784..2021	CDD:350402