DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptp61F and Ptpmeg2

DIOPT Version :9

Sequence 1:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_572576.1	Gene:	Ptpmeg2 / 31907	FlyBaseID:	FBgn0028341	Length:	827	Species:	Drosophila melanogaster

Alignment Length:	324	Identity:	114/324 - (35%)
Similarity:	168/324 - (51%)	Gaps:	39/324 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QIEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLKRG 82
            ||....|.:|.  |...||..:..:| |.|..|  ..:....|...|||.||..|||||:||...
  Fly   520 QIVQMVKQRGR--HGLIKEYADIRNR-APEGTF--LHARMRANLTKNRYTDVLCYDHSRVVLAHE 579

  Fly    83 S----VDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHL 143
            .    .||||||.|...:.:..||.|||||..|...||.|:|||....::|..::||:.::||..
  Fly   580 DGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQ 644

  Fly   144 YW-PNEMGADKALKLP--HVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFG 205
            || |.|   :.:|:..  ||:    .:.:|..::::....:|.:::|.:.|.|..:.:|:|||:|
  Fly   645 YWEPTE---ESSLEFGDYHVR----TISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYG 702

  Fly   206 IPSSPNAFLKFLQQVRDSGC-LSRDVG----------PAVVHCSAGIGRSGTFCLVDCCLVLIDK 259
            :|||..|.|.|||:||:... |.:.:|          |.||||||||||:|||..:|.|:..::.
  Fly   703 VPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLED 767

  Fly   260 YGECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIE-----GIKKLHDPTFLDAEEPLISNDTE 318
            .|..::...:.::||.|...||..||..|.:.|:||     |:.:..|....|..||    |:|
  Fly   768 VGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQTVDLAGFDEREP----DSE 827

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	100/278 (36%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	93/250 (37%)
Ptpmeg2	NP_572576.1	CRAL_TRIO_N	<114..144	CDD:215024
		SEC14	170..314	CDD:238099
		Y_phosphatase	557..803	CDD:278528	94/252 (37%)
		PTPc	559..803	CDD:238006	93/250 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443546
Domainoid	1	1.000	133	1.000	Domainoid score	I1104
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000704
OrthoInspector	1	1.000	-	-		otm46470
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840