Protein Alignment Ptp61F and PTPN20

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_054221455.1
• Gene: PTPN20 / 26095
• HGNCID: 23423
• Length: 481
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 60/264 - (22%)
• Similarity: 78/264 - (29%)
• Gaps: 119/264 - (45%)

  Fly    47 TEDDRIRIFRPDQNALRMQTGAERLCMTPPTLEQFVEAVKQTVLANKKWVPPPGKGTLYIRPLLL 111
            |:|||             .:.|......||| :.|:|                |.||.....:||
Human   116 TQDDR-------------GSWASTANTVPPT-QPFLE----------------GGGTRKQDCVLL 150

  Fly   112 GSGAT------------------LGV------APAPEYTFLIYASPVGDYHKVSSGLNLKVDHKY 152
            .|..|                  |.|      .|||:|  |.:..|.||          .|||
Human   151 ASEGTQVMRNGDSRAPSEAESFALEVQDHVFQIPAPDY--LQHWGPAGD----------NVDH-- 201

  Fly   153 HRAHSGGTGGVKSCTNYSPVVKSLLEAKS--------------AGFS-----DVLFLDAATGRNI 198
                     ..|.|     |.|:..|.:|              ..||     |.|..|..|
Human   202 ---------NEKDC-----VFKNHTEDESLEGIQPPVGEHGLNTPFSVRRSWDSLNEDVET---- 248

  Fly   199 EELTACNIFIVKGNIVSTPPTSGTILPGVTRKSISELAH----DIGYQVEERDVSVDELLEAEEV 259
            |.|:.|  |..||.:.:        :|.|...:..|..|    |...::.:.|.:|.|.|.|.|.
Human   249 EVLSIC--FNEKGPVHA--------MPVVDSGNRQEDTHGSDGDGDGEIVDEDAAVAEALAALEA 303

  Fly   260 FCTG 263
            ...|
Human   304 ATAG 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	56/248 (23%)
PTPN20	XP_054221455.1	PTPc-N20	269..475	CDD:350444	10/39 (26%)