Protein Alignment Ptp61F and Ptpn18

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_035336.2
• Gene: Ptpn18 / 19253
• MGIID: 108410
• Length: 453
• Species: Mus musculus
• Alignment Length: 347
• Identity: 110/347 - (31%)
• Similarity: 159/347 - (45%)
• Gaps: 36/347 - (10%)

  Fly    18 QIEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVL--- 79
            |:||....:|....|.:.:|.........|...||....|..|...|||:||..||.:|::|
Mouse    14 QLEARDYREGAILAREFSDIKARSVAWKSEGVCSTKAGSRLGNTNKNRYKDVVAYDETRVILSLL 78

  Fly    80 -KRGSVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHL 143
             :.|..||||||.::.....:.||.|||||..|:..||.:|||...:.:||..:..|..:.||..
Mouse    79 QEEGHGDYINANFIRGIDGSQAYIATQGPLPHTLLDFWRLVWEFGVKVILMACQETENGRRKCER 143

  Fly   144 YWPNEMGADKALKLPHVKLTVEL-----VRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPD 203
            ||..|....||... .:.||.|.     :.|.|.|...::.|          |.|.|..|.:|||
Mouse   144 YWAREQEPLKAGPF-CITLTKETTLNADITLRTLQVTFQKEF----------RSVHQLQYMSWPD 197

  Fly   204 FGIPSSPNAFLKFLQQVRDSGCL-SRDVGPAVVHCSAGIGRSGTFCLVDCC-LVLIDKYGECNVS 266
            .|:|||.:..|..:::.|   || ....||..||||||.||:|..|.||.. .:|:.:....|.|
Mouse   198 HGVPSSSDHILTMVEEAR---CLQGLGPGPLCVHCSAGCGRTGVLCAVDYVRQLLLTQTIPPNFS 259

  Fly   267 --KVLCELRSYRMGLIQTADQLDFSYQAIIEGIKK-LHD--PTFLDAEE---PLISNDTETHTLD 323
              :|:.|:|..|...:||.:|..|.|..:.:...: |.|  |.:.:.:|   |:........|..
Mouse   260 LFQVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFSRTLQDTSPHYQNLKENCAPICKEAFSLRTSS 324

  Fly   324 ELPPPLPPR---VQSLNLPLAP 342
            .||....|.   ::|:::|..|
Mouse   325 ALPATSRPPGGVLRSISVPAPP 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	86/240 (36%)
Ptpn18	NP_035336.2	PTP_DSP_cys	27..292	CDD:475123	94/278 (34%)
		PRK12323	<331..>452	CDD:481241	4/16 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..453