DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp61F and K07F5.6

DIOPT Version :9

Sequence 1:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_501764.2	Gene:	K07F5.6 / 177832	WormBaseID:	WBGene00010634	Length:	470	Species:	Caenorhabditis elegans

Alignment Length:	365	Identity:	72/365 - (19%)
Similarity:	127/365 - (34%)	Gaps:	120/365 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 EKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLKRGSVD---------YINANLVQLERAERQYI 102
            ||..|.:.|:.|.   ||        |::|::|...:.:         ||||:.::.:.:::::|
Worm   133 EKSLSKNRSKNHK---LN--------DNTRVILSPENTENSRTDPPDTYINASHIKFDNSQKEFI 186

  Fly   103 LTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTV--- 164
            :||.||.|||..||.||            .:|:..|| ..::.|....|.:..:.|.:.|..
Worm   187 VTQYPLPDTVRDFWRMV------------SIMKVTQI-VTIFEPQTDEAIEEFRNPTLTLAAPAP 238

  Fly   165 --------------------------ELVRLET--------------YQNFVRRWFKLTDLETQQ 189
                                      :.:|.|:              |.| ::.|...|...|..
Worm   239 TSTMTTIGGFPVPIGQIAHNRDQIQGQSIRCESNVHRSSFFPLETDHYMN-LKGWLINTRRVTVD 302

  Fly   190 SR----------EVMQ-----------FHYTTWPDFGIPSSPNAFLKFLQQVRDSGCLS-----R 228
            .|          ||:.           ::.||||....|......|..::........|     .
Worm   303 HRNKGWMNKYTVEVVAEGCSEATFAKVYNCTTWPWKKYPDDEKKVLALVRAPYKDTSTSLIANLE 367

  Fly   229 DVGPAVVHCSAGIGRSGTFCLVDCCL--VLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQ 291
            .:.|.||.|..|:.||.|..|....:  ::..|..:|:.  :..::|..|.|:...:....::.:
Worm   368 KLAPIVVMCDLGLDRSATVVLTSIIIDQIIAGKTPDCDA--LFKKMRDQRAGVFTMSIFYTYAIR 430

  Fly   292 AIIEGIK-KLHDPTFLDAEE------------PLISNDTE 318
            |.:..:| ||........||            |.::..|:
Worm   431 AALFYMKIKLQTMNDAGGEEMQTMLNSALAKVPFVTKKTK 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	65/327 (20%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	60/312 (19%)
K07F5.6	NP_501764.2	eIF1_SUI1_like	<30..>110	CDD:294159
		PTPc	111..434	CDD:214550	65/327 (20%)
		PTPc	138..433	CDD:304379	62/321 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810