Protein Alignment Ptp61F and ptpn-22

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_500128.2
• Gene: ptpn-22 / 176981
• WormBaseID: WBGene00021507
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 403
• Identity: 107/403 - (26%)
• Similarity: 182/403 - (45%)
• Gaps: 73/403 - (18%)

  Fly    16 RLQIEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLK 80
            :|::||||:.:              |           :.:.:|..|  |||||:.|||.:|:.::
 Worm   109 KLRMEAEYRSE--------------C-----------AVAPQHYAR--NRYRDILPYDKNRVEIQ 146

  Fly    81 RGSVD---YINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCH 142
            :.|.:   |:||:|:||...:.::|..|.||..|:..:|.|:.|.:...|::|.||:|..:|||.
 Worm   147 KDSENPEGYMNASLIQLPGGKTEFIAAQAPLPATLDEWWKMIDEHRVSLVVILCKLVELNKIKCE 211

  Fly   143 LYWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIP 207
            .|||.::|..:.  ....::|:|..:|.....::.|..|:.:..|.:.|:|.|.||..|||.|.|
 Worm   212 RYWPEQVGESEL--FGDYEITLEEEKLFDDDEYLMRCLKMENQTTGECRKVHQLHYREWPDHGCP 274

  Fly   208 SSPNAFLKFLQQVRD--SGCLSRDVGPAVVHCSAGIGRSGTFCLVDC--------CLVLIDKYGE 262
            |.....|..:..:.:  .....:|..|.:||||||:||:||...::.        .|..||.:|
 Worm   275 SGEKQLLNMIDLMENIHEEVSPQDSSPILVHCSAGVGRTGTIIAINFIREQMKAETLHSIDIFG- 338

  Fly   263 CNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEGIKK----LHDPTFLDAEEPLISNDT---ETH 320
                 ::..||..|..::||.||..|.::.|....::    :.:|. ||...|:.:.|.   .:.
 Worm   339 -----LVMTLRKQRASMVQTQDQFQFVHRCIASYCRRHLGIIEEPK-LDLAPPVATADLPVGSSG 397

  Fly   321 TLDELPPPLPPRVQSLNLPLAPNSGGILSLNMRAAQANGAESIGKELSKDALNNFINQHDMIHDA 385
            ::..:.||.|     ...|....:..|.:.|    |.:..:|....:.:|....        ..|
 Worm   398 SVRLIAPPTP-----TTGPSTDQTATIANYN----QLHHHQSSSNHMDEDTSTE--------EAA 445

  Fly   386 EVADSRPLPPLPV 398
            .|.|....||.|:
 Worm   446 SVPDFPEEPPAPM 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	78/240 (33%)
ptpn-22	NP_500128.2	PTPc	102..365	CDD:214550	86/290 (30%)