DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp61F and Ptprg

DIOPT Version :9

Sequence 1:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_599183.2	Gene:	Ptprg / 171357	RGDID:	620774	Length:	1442	Species:	Rattus norvegicus

Alignment Length:	374	Identity:	116/374 - (31%)
Similarity:	170/374 - (45%)	Gaps:	68/374 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 TSESERH-TNRGLNRYRDVNPYDHSRIVLK------RGSVDYINANLVQLERAERQYILTQGPLV 109
            |:|...| .|:..|||.::..|||||:.|:      ....||||||.|......:.||.|||||.
  Rat   862 TAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLK 926

  Fly   110 DTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETYQN 174
            .|...||.|:|||.:..::|:..|:||.:.||..|||.|...:      :..:.|.|...|.:..
  Rat   927 STFEDFWRMIWEQNTGIIIMITNLVEKGRRKCDQYWPTENTEE------YGNIIVTLKSTEVHAC 985

  Fly   175 FVRRWFKLTDLET-----------QQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVRDSGCLSR 228
            :..|.|.:.:.:.           |..|.|:|:|||.|||.|:|......|.|::  |.|.....
  Rat   986 YTVRRFSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVR--RSSAARMP 1048

  Fly   229 DVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQAI 293
            |:||.:||||||:||:||:.::|..|..|......||...|..:|:.|..|:||.:|..|.:.|:
  Rat  1049 DMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDAL 1113

  Fly   294 IEGIKKLHDPTFLDAEEPLISNDTETHTLDELPPPLPPRVQSLNLPLAPNSGG----------IL 348
            :|.|        |..|..:.|:...::               :|..|.|..||          |.
  Rat  1114 LEAI--------LGKETEVSSSQLHSY---------------VNSILIPGVGGKTRLEKQFKLIT 1155

  Fly   349 SLNMRAAQANGAESIGKELSKDALNNFINQHDMIHDAEVADSRPLPPLP 397
            ..|.:..:...|:   ||.:|:.     |::..:..||.| ...|.|||
  Rat  1156 QCNAKYVECFSAQ---KECNKEK-----NRNSSVVPAERA-RVGLAPLP 1195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	92/260 (35%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	88/249 (35%)
Ptprg	NP_599183.2	alpha_CARP_receptor_like	67..319	CDD:239396
		FN3	348..438	CDD:238020
		R-PTPc-G-1	845..1118	CDD:350505	94/271 (35%)
		R-PTP-G-2	1202..1406	CDD:350508
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810