Protein Alignment Ptp61F and Ptpn2

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_008770303.1
• Gene: Ptpn2 / 117063
• RGDID: 620710
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 176/536 - (32%)
• Similarity: 253/536 - (47%)
• Gaps: 149/536 - (27%)

  Fly    14 AARLQIEAEYKDKGPQWHRFYKEI-CETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRI 77
            :|.::.|.|..|...:|...|.|| .|:.|...:..:|.       .||..||||||:||||||:
  Rat     2 SATIEREFEELDAQCRWQPLYLEIRNESHDYPHRVAKFP-------ENRNRNRYRDVSPYDHSRV 59

  Fly    78 VLKRGSVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCH 142
            .|:....|||||:||.:|.|:|.||||||||.:|..|||||||:||:|||:|||:.:||:.:||.
  Rat    60 KLQSAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTRAVVMLNRTVEKESVKCA 124

  Fly   143 LYWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIP 207
            .|||.:   |:.:.......:|:|:..:....:.....:|.::.:.::|.:..||||||||||:|
  Rat   125 QYWPTD---DREMVFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVP 186

  Fly   208 SSPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLCEL 272
            .||.:||.||.:||:||.|:.|.||||:||||||||||||.|||.||||::|..:.||.::|..:
  Rat   187 ESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGEDVNVKQILLSM 251

  Fly   273 RSYRMGLIQTADQLDFSYQAIIEGIKKLHDPTFLDAEEPLISNDTETHTLDELPPPLPPRVQSLN 337
            |.||||||||.|||.|||.|||||.|                     :|
  Rat   252 RKYRMGLIQTPDQLRFSYMAIIEGAK---------------------YT---------------- 279

  Fly   338 LPLAPNSGGILSLNMRAAQANGAESIGKELSKDALNNFINQHDMIHDAEVADSRPLPPLPVRAFN 402
                                                                             
  Rat   280 ----------------------------------------------------------------- 279

  Fly   403 DSDSDEDYLLDDDDEDDTDEDEEYETINEHDADPVNGHVPATTQPHADDVNANNEKPAVPVDEQH 467
                          :.|::..:.::.:::.|..||..|    :|........|.::..   .|..
  Rat   280 --------------KGDSNIQKRWKELSKEDLSPVCDH----SQNRTMTEKYNGKRIG---SEDE 323

  Fly   468 KANGI-DPIPGQLPASPENELKRRKRNEYQASLEQKVNDMKRKQRENEDKQLAAKKR----RSLL 527
            |..|: ..:|..:..|.|:.|::|.|.:.:|:..|||..|:::..|.|.|    :||    :.:|
  Rat   324 KLTGLSSKVPDTVEESSESILRKRIREDRKATTAQKVQQMRQRLNETERK----RKRWLYWQPIL 384

  Fly   528 T------YIAAGVVVG 537
            |      .|..|.:||
  Rat   385 TKMGFVSVILVGALVG 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	123/227 (54%)
Ptpn2	XP_008770303.1	PTP_DSP_cys	19..272	CDD:475123	132/262 (50%)