Protein Alignment Ptp61F and ptpn18

DIOPT Version :10

• Sequence 1: NP_476687.1
• Gene: Ptp61F / 38160
• FlyBaseID: FBgn0267487
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_031746899.1
• Gene: ptpn18 / 101730699
• XenbaseID: XB-GENE-5829021
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 124/476 - (26%)
• Similarity: 188/476 - (39%)
• Gaps: 128/476 - (26%)

  Fly    34 YKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVL-----KRGSVDYINANLVQ 93
            ::||........||..|:|.......|...|||:|:.|||.:|:.:     :.|| |||||:.::
 Frog    31 FQEIRAQAGAFHKESDFTTEVGGSPENLKKNRYKDILPYDQTRVPVTFLSEEEGS-DYINASFIK 94

  Fly    94 LERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLP 158
            .....|.||.|||||..|:..||.|||:.:.:.::|..:.:|..:.||..|||.:.....|...|
 Frog    95 GTDPGRGYIATQGPLPHTIQDFWRMVWQYQVKVIVMACREVEHGKRKCERYWPLDDATTPAQFGP 159

  Fly   159 HV--KLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQV- 220
            ..  ||....|..|.....:|..|:      ::||::..|.|..|||.|||.|.:.||:.:|.|
 Frog   160 FTISKLEKNRVNAEVIYRKLRVTFR------EESRDISHFQYVAWPDRGIPDSYSCFLEMIQLVP 218

  Fly   221 ---RDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKY---GECNVSKVLCELRSYRMGL 279
               |:|..      |..||||||.||:|..|:|:....|:.:.   .:.::...:.::|..|...
 Frog   219 QYQRESRV------PLCVHCSAGCGRTGVICMVEYIQSLLQRQRVPADFSIFNAVLQMRRQRPSA 277

  Fly   280 IQTADQLDFSYQAI-------------IEGIKKLHDPTFLDAEEPLISNDTETHTLDELPP--PL 329
            :||.:|.:|.|.|:             .|.:|:...|.:.||...|       ..|.:|||  ..
 Frog   278 VQTQEQYEFLYHAVTEMFDKELQTSRCYENLKEDKSPLYDDATSVL-------SALRQLPPQRKK 335

  Fly   330 PPRVQSLNLPLAPNSGGILSLNMRAAQ-----ANGAESIGKELSKDALNNFINQHDMIHDAEVAD 389
            ||    ..||:......:.:...|..|     ||...::                       |..
 Frog   336 PP----ARLPIGAEYPPLCAPEQRPGQMPAMSANETYAV-----------------------VQK 373

  Fly   390 SRPLPPLPVRAFNDSDSDEDYLLDDDDEDDTDEDEEYETINEHDADPVNGHVPATTQPHADDVNA 454
            .||:.|                      :...:..:|:.:..|    |..|||.
 Frog   374 KRPVAP----------------------ETRPQTVQYDNVPTH----VPTHVPT----------- 401

  Fly   455 NNEKPAVPVDE-----QHKAN 470
                || |:|:     .||.|
 Frog   402 ----PA-PLDQLYSTVTHKGN 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc-N1_2	63..291	CDD:350393	80/241 (33%)
ptpn18	XP_031746899.1	PTP_DSP_cys	30..295	CDD:475123	89/276 (32%)