DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp61F and ptpn9a

DIOPT Version :9

Sequence 1:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_005163030.1	Gene:	ptpn9a / 100526653	ZFINID:	ZDB-GENE-101027-1	Length:	571	Species:	Danio rerio

Alignment Length:	276	Identity:	97/276 - (35%)
Similarity:	144/276 - (52%)	Gaps:	24/276 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 YKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLK---RGSVDYINANLVQLE 95
            |:|:    .||.....|:.:.:..:..|  |||.||...|.:|:.||   ....|||||:.:...
Zfish   294 YEEL----RREQPPGTFTCALAAHNQER--NRYGDVLCLDQTRVRLKARRNERSDYINASFMDGY 352

  Fly    96 RAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHV 160
            :.:..||.|||||..|.|.||.|||||....::|..:..|..:.||..|||.|.|..:.    :.
Zfish   353 KQKNAYIGTQGPLEKTYGDFWRMVWEQNVLVIVMTTRTDEGGRRKCGQYWPQEEGGQEV----YG 413

  Fly   161 KLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVRDS-- 223
            .:.|...|::.:.::.:...:|.:.||.:.|:|..|.:.:|||:|:|||..:.:.||..|:..
Zfish   414 YIAVVNHRVDNHAHYNQTTLELHNTETFEQRQVTHFQFLSWPDYGVPSSAVSLIDFLGAVKHQQQ 478

  Fly   224 ------GCLSR--DVG-PAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLCELRSYRMGL 279
                  |...|  .:| |.||||||||||:||||.:|.||..:...|..|:.:.:..:||.|...
Zfish   479 WAVQAFGTQWRGHPLGPPMVVHCSAGIGRTGTFCALDICLSQLQDVGTLNICQTVRRMRSQRAFS 543

  Fly   280 IQTADQLDFSYQAIIE 295
            |||.:|..|.:.||:|
Zfish   544 IQTPEQYYFCHAAILE 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	96/274 (35%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	90/246 (37%)
ptpn9a	XP_005163030.1	CRAL_TRIO_N	11..59	CDD:215024
		SEC14	85..228	CDD:238099
		PTPc	289..559	CDD:214550	96/274 (35%)
		PTPc	316..559	CDD:238006	91/248 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000704
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.870