DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp61F and ptprz1

DIOPT Version :9

Sequence 1:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001362251.1	Gene:	ptprz1 / 100125091	XenbaseID:	XB-GENE-1011831	Length:	2281	Species:	Xenopus tropicalis

Alignment Length:	415	Identity:	116/415 - (27%)
Similarity:	178/415 - (42%)	Gaps:	86/415 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 RFYKEICETCDREAKEKQFS-----------TSESERH-TNRGLNRYRDVNPYDHSRIVL----- 79
            :|.|.:.|...|.....:|.           ||::..| .|:..|||.::..|||||:.|
Frog  1676 QFPKHVEELHSRNGFTDEFEEIQNCTADLGITSDNSNHPDNKNKNRYVNIVAYDHSRVKLSQLGE 1740

  Fly    80 KRG-SVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHL 143
            |.| :.||||||.|.....::.||..||||..|...||.|:||.....::|:..|:||.:.||..
Frog  1741 KEGKATDYINANFVDGYNKQKAYIAAQGPLKSTAEDFWRMLWEHNVEVIVMITNLVEKGRRKCDQ 1805

  Fly   144 YWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKL---TDLETQQSREVMQFHYTTWPDFG 205
            |||:: |:::...........:::...|.:.|:.|..|:   :.......|.|:|:|||.|||.|
Frog  1806 YWPSD-GSEEYGSFLVTHKNTKVLAYYTVRTFILRNNKIKKGSQKGRHNERTVVQYHYTQWPDMG 1869

  Fly   206 IPSSPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLC 270
            :|......|.|:::...:.|...  ||.|||||||:||:||:.::|..|..|...|..|:...|.
Frog  1870 VPEYTLPVLTFVRKASATKCNGN--GPVVVHCSAGVGRTGTYIVLDSMLKQIQHEGTVNIFGFLK 1932

  Fly   271 ELRSYRMGLIQTADQLDFSYQAIIEGI----------------------------------KKLH 301
            .:||.|..|:||.:|..|.:.|::|.|                                  |.|.
Frog  1933 HIRSQRNYLVQTEEQYIFIHDALVEAILSRETEVPESHIHGYVNTLLTTGPSGKSRLETQFKLLS 1997

  Fly   302 DPTFLDAEEPLISNDTETHTLDELPPPLPPRVQSLN-----LPLAPNSGGILSLNMRAAQANGAE 361
            :|..|..:..:               .|.|:.:..|     :|:..:..|:.||     ...|.:
Frog  1998 EPNILQCDYSM---------------ALKPQNRDKNRTSSIIPVERSRVGLSSL-----AGEGTD 2042

  Fly   362 SIGKE--LSKDALNNF-INQHDMIH 383
            .|...  :.....|.| |.||.::|
Frog  2043 YINASYVMGYHESNQFIITQHPLLH 2067

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	94/281 (33%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	86/241 (36%)
ptprz1	NP_001362251.1	alpha_CARP_receptor_like	45..298	CDD:239396
		fn3	313..395	CDD:365830
		PTP_DSP_cys	1690..1960	CDD:391942	92/272 (34%)
		R-PTP-Z-2	2043..2246	CDD:350507	7/25 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910