DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2199 and Zfp689

DIOPT Version :9

Sequence 1:NP_728599.1 Gene:CG2199 / 38159 FlyBaseID:FBgn0035213 Length:733 Species:Drosophila melanogaster
Sequence 2:NP_780372.2 Gene:Zfp689 / 71131 MGIID:1918381 Length:500 Species:Mus musculus


Alignment Length:275 Identity:54/275 - (19%)
Similarity:89/275 - (32%) Gaps:65/275 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   229 QCPECEFHAKFPKPYKEHLQKEHGLQRPRIYPCTLCIKTFGVLKTLKNHLRDTHS---------- 283
            |||.|.....:|.....| |:.|..::|  |.|..|.:.|.....|..|.| .|:          
Mouse   262 QCPSCGRRFAYPSLLAIH-QRTHTGEKP--YTCLECSRRFRQRTALVIHQR-IHTGEKPYPCPDC 322

  Fly   284 -RTFESEAKTKAKESKEKEAKSGAKNKIDAKAKETNAVSQR------KKPKEKKSKEKKTEIKCN 341
             |.|.|.::..:........:..|....:|:..:.:.:.|.      :||           ..| 
Mouse   323 ERRFSSSSRLVSHRRVHSGERPYACENCEARFSQRSTLLQHQLLHTGEKP-----------YPC- 375

  Fly   342 VETKVVDEIDDQVNNKKGTDSEDADQTQATKIASFKALNESLMKKRMLENVIDSEYTFAINGSSA 406
                                   .|..:|.:.:...|::.|...:..|....|....||.....|
Mouse   376 -----------------------PDCGRAFRRSGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLA 417

  Fly   407 STPRADSNN--FQCEICDCELMTAKQMQEHMKTVHSIDKPKVFKCHVCEKSLATKQSLKTHMTLH 469
            |..|..|..  :.|::|.........:.:| :.:|:.:||  |.|..|.:....:.||..|... 
Mouse   418 SHRRVHSGERPYACDLCSKRFAQWSHLSQH-QLLHTGEKP--FPCLECGRCFRQRWSLAVHKCC- 478

  Fly   470 ADGAEAPNSSKRKIL 484
               ...||.|.|.::
Mouse   479 ---PNTPNGSPRPLI 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2199NP_728599.1 C2H2 Zn finger 418..439 CDD:275370 3/20 (15%)
C2H2 Zn finger 449..469 CDD:275370 5/19 (26%)
Zfp689NP_780372.2 KRAB 29..88 CDD:214630
KRAB 29..68 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 105..144
C2H2 Zn finger 151..171 CDD:275368
COG5048 171..>466 CDD:227381 47/245 (19%)
C2H2 Zn finger 179..199 CDD:275368
C2H2 Zn finger 207..227 CDD:275368
zf-H2C2_2 219..244 CDD:290200
C2H2 Zn finger 235..255 CDD:275368
zf-H2C2_2 247..272 CDD:290200 4/9 (44%)
C2H2 Zn finger 263..283 CDD:275368 6/20 (30%)
zf-H2C2_2 276..300 CDD:290200 8/26 (31%)
C2H2 Zn finger 291..311 CDD:275368 6/20 (30%)
zf-H2C2_2 303..328 CDD:290200 6/25 (24%)
C2H2 Zn finger 319..339 CDD:275368 3/19 (16%)
zf-H2C2_2 332..356 CDD:290200 2/23 (9%)
C2H2 Zn finger 347..367 CDD:275368 2/19 (11%)
zf-H2C2_2 360..384 CDD:290200 6/58 (10%)
C2H2 Zn finger 375..395 CDD:275368 5/43 (12%)
C2H2 Zn finger 403..423 CDD:275368 6/19 (32%)
zf-H2C2_2 416..440 CDD:290200 6/23 (26%)
C2H2 Zn finger 431..451 CDD:275368 3/20 (15%)
C2H2 Zn finger 459..475 CDD:275368 4/15 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167832291
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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