Protein Alignment CG2199 and ZNF181

DIOPT Version :9

• Sequence 1: NP_728599.1
• Gene: CG2199 / 38159
• FlyBaseID: FBgn0035213
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: XP_016882229.1
• Gene: ZNF181 / 339318
• HGNCID: 12971
• Length: 585
• Species: Homo sapiens
• Alignment Length: 601
• Identity: 111/601 - (18%)
• Similarity: 203/601 - (33%)
• Gaps: 166/601 - (27%)

  Fly   162 KKQISRLFEDNLNDSVKLTPAKEVSSTKKAFLNLFGNGGNDAIEVLTESEEEEDSDKGPITINTN 226
            :|::|:.:|....:       ||:|:.|..:                    :|||   |.|:...
Human    85 EKKLSKDWESRWEN-------KELSTKKDNY--------------------DEDS---PQTVIIE 119

  Fly   227 NFQCPECEF-HAKFPKPYKEHLQKEHGLQRPRIYPCTLCIKTFGVLKTL--KNHLRDT-HSRTFE 287
            .......|| ::|....|.|.|:.:||.|.....|..|..:......::  .|..|.| ||::..
Human   120 KVVKQSYEFSNSKKNLEYIEKLEGKHGSQVDHFRPAILTSRESPTADSVYKYNIFRSTFHSKSTL 184

  Fly   288 SEAKTKAKESKEKEAKSGAKNKIDAKAKETNAVSQRKKPKEKKSKEKKTEIKCNVETKVVDEIDD 352
            ||        .:|.:..|..:|.|        :.::..||:...|.:|.    |...|:::
Human   185 SE--------PQKISAEGNSHKYD--------ILKKNLPKKSVIKNEKV----NGGKKLLN---- 225

  Fly   353 QVNNKKGT-----DSEDADQT-QATKIASFKALNESLMKKRMLE-----NVIDSEY-------TF 399
              :||.|.     .|....|| ...||.:.....::..|:.:|.     :..:..|       ||
Human   226 --SNKSGAAFSQGKSLTLPQTCNREKIYTCSECGKAFGKQSILNRHWRIHTGEKPYECRECGKTF 288

  Fly   400 AINGSSAS---TPRADSNNFQCEICDCELMTAKQMQEHMKTVHSIDKPKVFKCHVCEKSLATKQS 461
            : :|||.:   ...:....::|..|.........:..|..| |:.:||  ::|..|.||.:....
Human   289 S-HGSSLTRHLISHSGEKPYKCIECGKAFSHVSSLTNHQST-HTGEKP--YECMNCGKSFSRVSH 349

  Fly   462 LKTHMTLHADGAEAPNSSKRKILQDEDEDVDILGTTQIENTA----EKVEGPKKSQQSPTKAAKF 522
            |..|:.:|.              |::..:..|.|...|..::    :|:...:|..:.......|
Human   350 LIEHLRIHT--------------QEKLYECRICGKAFIHRSSLIHHQKIHTGEKPYECRECGKAF 400

  Fly   523 TNRKILQEEDEVVEIVDAFKTDNTAEDDEGPAEEKIIRSRN-NIQHQVDGGMIAPRSPAKKTKKT 586
            .....|.....:..:...::.:...         |:..|.: .:|||
Human   401 CCSSHLTRHQRIHTMEKQYECNKCL---------KVFSSLSFLVQHQ------------------ 438

  Fly   587 SHVDLSVSTTNGNSPAKSEKRKKQDKSEDTLPSSDVDIVEEINYNVRPHKKARLESIGDSTADES 651
                 |:.|.  ..|.:.:|.:|           ..:.:|.:|.::|.|.:.:
Human   439 -----SIHTE--EKPFECQKCRK-----------SFNQLESLNMHLRNHIRLK------------ 473

  Fly   652 TLSCDRCGKFVKSRQRLDSHMEKKHAAK--LQCTLCKEVYQNQMDYVAHFSNCGSEGGLPCGVAN 714
            ...|..|||....|..|..| .:.|..:  .:|..|.:.:....:...|......|....|.  .
Human   474 PYECSICGKAFSHRSSLLQH-HRIHTGEKPYECIKCGKTFSCSSNLTVHQRIHTGEKPYKCN--E 535

  Fly   715 CKKVFTEANFLSSHLR 730
            |.|.|::.:.|::|.|
Human   536 CGKAFSKGSNLTAHQR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2199	NP_728599.1	C2H2 Zn finger	418..439	CDD:275370	4/20 (20%)
		C2H2 Zn finger	449..469	CDD:275370	6/19 (32%)
ZNF181	XP_016882229.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142429
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930