DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2199 and CG8944

DIOPT Version :9

Sequence 1:	NP_728599.1	Gene:	CG2199 / 38159	FlyBaseID:	FBgn0035213	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_573065.1	Gene:	CG8944 / 32517	FlyBaseID:	FBgn0030680	Length:	762	Species:	Drosophila melanogaster

Alignment Length:	283	Identity:	53/283 - (18%)
Similarity:	91/283 - (32%)	Gaps:	67/283 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 FQCPECEFHAKFPKPYKEHLQKEHGLQRPRIYPCTLCIKTFGVLKTLKNHLRDTHSRTFESEAKT 292
            :.|..|.......:.:..|.|...|......:.|.||..:|........|||..:...|   ..:
  Fly   504 YYCNICSIQFHNAQEFDNHKQLHLGGVTEIKFNCELCTASFREKANYDEHLRRHNEELF---LPS 565

  Fly   293 KAKESKEKEAKSGAKNKIDAKAKETNAVSQRKKPKEKKSKEKKTEIKCNVETKVVDEIDDQVNNK 357
            .|......|...| .::|..:.:|:.....|:|   ::...|.|:       .:||: ||::...
  Fly   566 LALNHSIMEGGLG-DDEIGVEGEESRGSGSRRK---RRHAAKATD-------DMVDD-DDRIGGG 618

  Fly   358 KGTDSEDA-------------------------------DQTQATKIASFKALNESLMKKRMLEN 391
            .|..|...                               |:.:......:...|:|.:.:..|..
  Fly   619 GGGGSGGGGTDIAKPYGCDVCRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKSFVARNSLFE 683

  Fly   392 VIDSEYTFAINGSSASTPRADSNNFQCEICDCELMTAKQMQEHMKTVHSIDKPKVFKCHVCEKSL 456
            .:...|:              :..|:|:||.....:.|.:|.| |.:|  ||.|.:.|.:|..:.
  Fly   684 HLKQHYS--------------NEEFKCDICGKTFKSTKNLQNH-KQIH--DKIKRYVCQICGSAF 731

  Fly   457 ATKQSLKTHMTLHADGAEAPNSS 479
            |....|..|...|    ..||.:
  Fly   732 AQAAGLYLHKRRH----NRPNGA 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2199	NP_728599.1	C2H2 Zn finger	418..439	CDD:275370	7/20 (35%)
CG2199	NP_728599.1	C2H2 Zn finger	449..469	CDD:275370	5/19 (26%)
CG8944	NP_573065.1	MADF_DNA_bdg	259..344	CDD:287510
		MADF	379..472	CDD:214738
		C2H2 Zn finger	476..496	CDD:275368
		C2H2 Zn finger	506..526	CDD:275368	4/19 (21%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	636..656	CDD:275368	0/19 (0%)
		zf-C2H2_8	639..712	CDD:292531	11/86 (13%)
		C2H2 Zn finger	666..688	CDD:275368	3/21 (14%)
		zf-C2H2	694..716	CDD:278523	8/22 (36%)
		C2H2 Zn finger	696..716	CDD:275368	7/20 (35%)
		zf-H2C2_2	708..733	CDD:290200	9/27 (33%)
		C2H2 Zn finger	724..744	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440030
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930