DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2199 and CG2129

DIOPT Version :9

Sequence 1:	NP_728599.1	Gene:	CG2199 / 38159	FlyBaseID:	FBgn0035213	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	77/397 - (19%)
Similarity:	142/397 - (35%)	Gaps:	83/397 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 SFVNG------ANTNTEIEIISASPKKLDKTPKKQISRLFEDNLNDSVKLTPAKEVSSTKK-AFL 193
            |||.|      .|.:.|..::...........|::..|..|.|       :|...|:.... |:.
  Fly    40 SFVFGDFLLHVQNIHFENGLLKTEATDAGANLKQERDREREPN-------SPVPIVAQVNPFAWY 97

  Fly   194 NLFGNGGNDAIE---VLTESEEEEDSDKGPITINTNNFQCPECEFHAK---FPKPYKEH------ 246
            .:.|:...|:.:   ||.:.:|:||...|...|...:.|....|...:   ....|||.
  Fly    98 EIGGDHNEDSDDERVVLEKQDEDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQEE 162

  Fly   247 ------LQKE--HGLQRPRIYPCTLCIKTFGVLKTLKNHLRDTHSRTFESEAKTKAKE---SKEK 300
                  |..|  |..:.|  :.|..|.|.:...|.|:.|:...|..|...:..::..:   .|:.
  Fly   163 CGMELDLDSEGRHSAKIP--HSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDA 225

  Fly   301 EAKSGAKNKIDAKAKETNAV-----SQRKKPKEKKSKEKK------TEIKCNVETKVVDEIDDQV 354
            ..||.|:   :.|.:....:     |.|:..|......::      |.::|..:...:..:|:.:
  Fly   226 PVKSAAQ---EYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHM 287

  Fly   355 NNKKGTDSEDADQTQATKIASFKALNESLMKKRMLENVID----------SEYTFAI----NGSS 405
            ....|        ..|..:...:......:|:..|::..:          .:..|.|    |...
  Fly   288 VQAHG--------GAACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNHGK 344

  Fly   406 ASTPRADSNNFQCEICDCELMTAKQMQEHMKTVHSIDKPKVFKCHVCEKSLATKQSLKTHMTLHA 470
            ..|   :..||.||.|.......:.::.|::: |:.::|  |.|.||:|...:...|:.||.:|:
  Fly   345 VHT---EQKNFVCESCGYSCRNKETLRVHIRS-HTGERP--FGCQVCDKRFPSHSGLREHMAMHS 403

  Fly   471 DGAEAPN 477
              .|.|:
  Fly   404 --TERPH 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2199	NP_728599.1	C2H2 Zn finger	418..439	CDD:275370	4/20 (20%)
CG2199	NP_728599.1	C2H2 Zn finger	449..469	CDD:275370	7/19 (37%)
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	2/19 (11%)
		zf-C2H2_8	323..411	CDD:292531	23/94 (24%)
		C2H2 Zn finger	327..346	CDD:275368	3/18 (17%)
		C2H2 Zn finger	354..374	CDD:275368	4/20 (20%)
		zf-H2C2_2	367..389	CDD:290200	8/24 (33%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-H2C2_2	395..419	CDD:290200	6/16 (38%)
		C2H2 Zn finger	410..430	CDD:275368
		C2H2 Zn finger	438..458	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457891
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930