DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2199 and mld

DIOPT Version :9

Sequence 1:NP_728599.1 Gene:CG2199 / 38159 FlyBaseID:FBgn0035213 Length:733 Species:Drosophila melanogaster
Sequence 2:NP_001247289.1 Gene:mld / 2768685 FlyBaseID:FBgn0263490 Length:1965 Species:Drosophila melanogaster


Alignment Length:487 Identity:93/487 - (19%)
Similarity:160/487 - (32%) Gaps:159/487 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 TITHRSIPSSLPIKI-----CFVCTS-------------TFMSSAALIEKVRETVDRVQEQPAKK 95
            |:..::.|:: |.||     |..|||             |..:...::......|.....||...
  Fly  1569 TVEMQASPTT-PRKILCCPDCEDCTSGHSHANEQFEELQTLQAPPTVLTPPSTIVSVPSPQPMVY 1632

  Fly    96 TKVAEIEEPSTQESDKKAVKVPKKNTTLRQ-RSKSIAAFPPSFVNGANTNTEIEIISASPKKLDK 159
            ::  .|..||.::|:      |...||||| |.:.:...|...::.|   |.:    |||     
  Fly  1633 SQ--HITMPSPEQSE------PDSTTTLRQYRKRGVIVGPQGPLHLA---TPV----ASP----- 1677

  Fly   160 TPKKQISRLFEDNLNDSVKLTPAKEVSSTKKAFLNLFGNGGNDAIEVLTESEEEEDSDKGPITIN 224
            :|....|....|::..:...|||........|..:        .::|   ||           :.
  Fly  1678 SPSSSPSSSTVDHIPPASPATPASPAPPPSPAVAS--------TVQV---SE-----------LR 1720

  Fly   225 TNNFQCPECEFHAKFPKPYKEHLQKEHGLQRPRIYPCTLCIKTFGVLKTLKNHLRDTHSRTFESE 289
            |:: .|..||.........|:|.|..||......|.||:|.:.:.:...|..|: ::|.      
  Fly  1721 TSH-HCLYCEERFTNEISLKKHHQLAHGALTTMPYVCTICKRGYRMRTALHRHM-ESHD------ 1777

  Fly   290 AKTKAKESKEKEAKSGAKNKIDAKAKETNAVSQRKKPKEKKSKEKKTEIKCNVETKVVDEIDDQV 354
                                ::.:..|.| :.:.:.|:..:....|..:....:....||...|.
  Fly  1778 --------------------VEGRPYECN-ICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQF 1821

  Fly   355 NNKKGTDSEDADQTQATKIASFKALNESLMKKRMLENVIDSEYTFAINGSSASTPRADSNNFQCE 419
                ||                    ||.:|..:           ..:|..         .:||:
  Fly  1822 ----GT--------------------ESALKTHI-----------KFHGEL---------GYQCD 1842

  Fly   420 ICDCELMTAKQMQEHMKTVHSIDKPKVFKCHVCEKSLATKQSLKTHMTLH--------ADGA-EA 475
            .||......|::::|.:| ||   ...:||..|..|.....:.:.||..|        .|.| ::
  Fly  1843 GCDRTFEYLKELRKHRRT-HS---EMFYKCKFCPSSFMRFTNFRAHMKTHLPLGVFRNEDAASKS 1903

  Fly   476 PNSSKRKILQDEDEDVDILGTTQIENTAEKVE 507
            |:::......|           ::||.|..:|
  Fly  1904 PSNNNSHASSD-----------KLENPATPIE 1924

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2199NP_728599.1 C2H2 Zn finger 418..439 CDD:275370 6/20 (30%)
C2H2 Zn finger 449..469 CDD:275370 5/19 (26%)
mldNP_001247289.1 zf-AD 186..255 CDD:214871
C2H2 Zn finger 1365..1388 CDD:275368
C2H2 Zn finger 1396..1416 CDD:275368
C2H2 Zn finger 1424..1445 CDD:275368
C2H2 Zn finger 1725..1746 CDD:275368 6/20 (30%)
C2H2 Zn finger 1756..1776 CDD:275368 5/20 (25%)
C2H2 Zn finger 1785..1806 CDD:275368 3/21 (14%)
C2H2 Zn finger 1814..1834 CDD:275368 8/54 (15%)
zf-C2H2 1839..1861 CDD:278523 7/22 (32%)
C2H2 Zn finger 1841..1861 CDD:275368 6/20 (30%)
C2H2 Zn finger 1868..1888 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45439978
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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