DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2211 and JMJD6

DIOPT Version :9

Sequence 1:	NP_001261251.1	Gene:	CG2211 / 38157	FlyBaseID:	FBgn0035211	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001074930.1	Gene:	JMJD6 / 23210	HGNCID:	19355	Length:	414	Species:	Homo sapiens

Alignment Length:	241	Identity:	50/241 - (20%)
Similarity:	80/241 - (33%)	Gaps:	79/241 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 LTMEEFA-----PHAYSSMPIIVKRAVAHWPAQKNLSFAFIKELYE-------------SVPGAM 176
            |::|||.     |:    .|:::..|...|.||:..:...:|..|.             ||...|
Human    54 LSVEEFVERYERPY----KPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKM 114

  Fly   177 DSDCQFLHFNSDLKSLKHVFSMS----AERSNLTQG--VPWFVGWSVCQPAVLAELRKLYPRPHF 235
            ....:::....|...| ::|..|    .:|..|.:.  ||.|....:.|.|  .|.|    ||
Human   115 KYYIEYMESTRDDSPL-YIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYA--GEKR----RP-- 170

  Fly   236 LPFDAEMPHTDFILMGYEQGAVMHLDYIPRLLWQAQLSGNKTWFLAPA----------------- 283
                   |:..|::.....|..:|:|.:....|.|.:.|:|.|.|.|.
Human   171 -------PYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQ 228

  Fly   284 -----------------PECDHQCQPFSFYVEPGDAVLVDTRIWYH 312
                             |....:.:|.....:||:.|.|... |:|
Human   229 QDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGG-WWH 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2211	NP_001261251.1	cupin_like	133..>306	CDD:304367	46/230 (20%)
JMJD6	NP_001074930.1	Nuclear localization signal 1. /evidence=ECO:0000269\|PubMed:14729065	6..10
		Nuclear localization signal 2. /evidence=ECO:0000269\|PubMed:14729065	91..95		1/3 (33%)
		Nuclear localization signal 3. /evidence=ECO:0000269\|PubMed:14729065	141..145		1/3 (33%)
		Nuclear localization signal 4. /evidence=ECO:0000269\|PubMed:14729065	167..170		1/6 (17%)
		JmjC	174..288	CDD:334913	19/101 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	336..403
		Nuclear localization signal 5. /evidence=ECO:0000269\|PubMed:14729065	373..378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000