Protein Alignment Myo61F and MYA2

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001190465.1
• Gene: MYA2 / 834412
• AraportID: AT5G43900
• Length: 1565
• Species: Arabidopsis thaliana
• Alignment Length: 989
• Identity: 349/989 - (35%)
• Similarity: 530/989 - (53%)
• Gaps: 97/989 - (9%)

  Fly    33 ERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLP-IYTDDHVKAYR 96
            |...:||.|...|. |..|...:.||..|:..:.||||.|.:||:|||:::|| :|:...:..|:
plant   118 EAPASGVDDMTRLA-YLHEPGVLQNLHSRYDINEIYTYTGSILIAVNPFRRLPHLYSSHMMAQYK 181

  Fly    97 NKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEG- 160
            .....|:.||.|||.|.|:|.:|.:...|.:|:|||||:||||::|.::::: |..|.:...||
plant   182 GASLGELSPHPFAVADAAYRQMINDGVSQSILVSGESGAGKTESTKLLMRYL-AYMGGRAAAEGR 245

  Fly   161 -VKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGG 224
             |:.|:|:|||||||||||||.||:|||||||:::||||.||...|..|..||||:|||......
plant   246 SVEQKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDEKGRISGAAIRTYLLERSRVCQVSDP 310

  Fly   225 ERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTK 289
            |||:|.||.|.|...|. :::.:||.. ..|.||.......:..||||:.:...::|:.|:..:.
plant   311 ERNYHCFYMLCAAPQED-VKKFKLEEP-KKYHYLNQSKCLELDSINDAEEYHATRRAMDVVGIST 373

  Fly   290 EEQREIFGIVASILHLGNVGFT---EVEGNAKVNSRDL--VVTAARLLGVNASELEAALTHRTID 349
            |||..||.:||:|||:||:.|.   |::.:...:.:.|  :.|||.||..:...||.:|..|.:.
plant   374 EEQDAIFSVVAAILHIGNIEFAKGEEIDSSIPKDDKSLFHLKTAAELLSCDEKALEDSLCKRIMV 438

  Fly   350 ARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISL-QAKETRASRNNVMGILDIYGFE 413
            .|.:.:|..|:.|.|..:||||||.:|.|||.|||.::|.|: |..:::    .::|:|||||||
plant   439 TRDETITKTLDPEAATLSRDALAKVMYSRLFDWLVDKINSSIGQDHDSK----YLIGVLDIYGFE 499

  Fly   414 IFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGII 478
            .|:.|||||||||..||||||.|.:...|.||:||::|.|.|..:|:.||:.|.:|||:|..|||
plant   500 SFKTNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYKKEEINWSYIEFVDNQDILDLIEKKPGGII 564

  Fly   479 SILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVN 543
            ::|||.|:.| ..|.:||.:||.|....|..:.         |..:.|.:|.:.||||:|||...
plant   565 ALLDEACMFP-RSTHETFAQKLYQTFKTHKRFT---------KPKLARSDFTICHYAGDVTYQTE 619

  Fly   544 GFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLKRPETAI-TQFRASLNNLMDILMCKEP 607
            .|||||.|.:..:.:..|:.:....|.:.||.....|.:...::| |:|:..|.:|::||...||
plant   620 LFLDKNKDYVIAEHQALLNSSSCSFVASLFPPMSDDSKQSKFSSIGTRFKQQLVSLLEILNTTEP 684

  Fly   608 SYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPN 672
            .||||||||:|....:|.:|.:|.|::..|:||.:|:..||:..|:.::.||.|:..|:....
plant   685 HYIRCIKPNNLLKPGIFENENILQQLRCGGVMEAIRISCAGYPTRKHFDEFLARFGILAPEVL-- 747

  Fly   673 YKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGL 737
            .|....| |..::|:..:|.  |.|::|:||:|:| ...:.|.:....|.....|:|||...:..
plant   748 VKNSDDP-AACKKLLDKVGL--EGYQIGKTKVFLR-AGQMADLDTRRTEVLGRSASIIQRKVRSY 808

  Fly   738 MQRRKYLKLRAQVIIMQSYCRRKLAQQAAK-KRREAAD-KIRAFIKGFITRNDAPNGFNEEFIAN 800
            :.::.::.||.....:||.||..||:...: .|||||. ||:..::.|:.|    ..:.|.:.|.
plant   809 LAKKSFIVLRNSAKQIQSVCRGYLARSVYEGMRREAAALKIQRDLRRFLAR----KAYTELYSAA 869

  Fly   801 AKRMWLLR---LAKEL----PTK--VLDKSWPHAPGHCEEASGILHRLH--RLHLARI-----YR 849
            ......:|   ..|||    .||  ::.::|      |.   |.|.|||  :|..|.|     :|
plant   870 VSVQAGMRGMVARKELCFRRQTKAAIIIQTW------CR---GYLARLHYRKLKKAAITTQCAWR 925

  Fly   850 LKLTPQQKRQFELKVLAEKVFKGKKNNYASSVS--TWFQEDRIPKEHIQRVNDFVASTFGSEQLK 912
            .|:...:.|:.::........:..||.....|.  ||    |:..|  :|:...:......|..|
plant   926 SKVARGELRKLKMAARETGALQAAKNKLEKQVEELTW----RLQLE--KRIRTDLEEAKKQESAK 984

  Fly   913 YQSF-------CTKFDRHGYKSRDRFILLSN-----KAIYVLDGKTYKQKHRLPLDKIDFTLTNH 965
            .||.       |.:.:....|.|:....::.     |.|.|:|.:.        :|||    ||.
plant   985 AQSSLEELQLKCKETEALLIKEREAAKKIAETAPIIKEIPVVDQEL--------MDKI----TNE 1037

  Fly   966 NDDLMVIRIPLDLK 979
            |:.|..:...|::|
plant  1038 NEKLKSMVSSLEMK 1051

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	269/664 (41%)
		Myosin_TH1	863..1049	CDD:461801	28/131 (21%)
MYA2	NP_001190465.1	Myosin_N	68..108	CDD:460670
		MYSc_Myo11	136..779	CDD:276835	269/664 (41%)
		IQ	889..911	CDD:197470	9/30 (30%)
		Myosin_tail_1	<935..>1111	CDD:460256	28/135 (21%)
		MyosinXI_CBD	1159..1535	CDD:271259