DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myo61F and XIH

DIOPT Version :9

Sequence 1:	NP_476934.2	Gene:	Myo61F / 38153	FlyBaseID:	FBgn0010246	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_194600.2	Gene:	XIH / 828991	AraportID:	AT4G28710	Length:	1516	Species:	Arabidopsis thaliana

Alignment Length:	1095	Identity:	354/1095 - (32%)
Similarity:	552/1095 - (50%)	Gaps:	169/1095 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLP-IYTDDHVKAYR 96
            |...:||.|...|. |..|...:.|:|.||..:.||||.|.:||:|||:::|| :|.:..::.|:
plant    57 EAPASGVDDMTRLA-YLHEPGVLQNMKSRFDINEIYTYTGNILIAVNPFRRLPHLYNNHMMQQYK 120

  Fly    97 NKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEG- 160
            ...|.|:.||.|||.|.|:|.:..:...|.:|:|||||:||||.:|.::|::|...|...: ||
plant   121 GAGFGELSPHPFAVADAAYRQMKNQGISQSILVSGESGAGKTETTKLLMQYLADMGGRAVS-EGR 184

  Fly   161 -VKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGG 224
             |:.|:|:|||||||||||||.||:|||||||:::||||.:|...|..|..||||:|||......
plant   185 TVEKKVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQRGRISGAAIRTYLLERSRVCQVSDP 249

  Fly   225 ERNFHIFYQLLAGADEALLQELRLERALD--TYSYLTDGLNGTVTRINDADSFKQVQQALTVIDF 287
            |||:|.||.|.|...|    :::..:..|  .:.||.......:.|::||..:::.::|:.|:..
plant   250 ERNYHCFYMLCAAPPE----DIKKWKLADPRKFHYLNQSQCIELERMDDAKEYRETRKAMDVVGI 310

  Fly   288 TKEEQREIFGIVASILHLGNVGF---TEVEGNAKVN--SRDLVVTAARLLGVNASELEAALTHRT 347
            ..|||..||.:||:|||||||.|   .|.:.:|..:  |...:.|||.|...:...||.:|..|.
plant   311 NSEEQEAIFQVVAAILHLGNVEFGKGKEADSSAPKDDTSNYHLKTAAELFMCDEQALEDSLCKRV 375

  Fly   348 IDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISL-QAKETRASRNNVMGILDIYG 411
            |..||:.:|..|:||.|..:||||||.||.|||.|:|.::|.|: |..::    ..::|:|||||
plant   376 IVTRGETITKCLDQESAALSRDALAKTVYSRLFDWIVNKINDSIGQDPDS----EYLIGVLDIYG 436

  Fly   412 FEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKG 476
            ||.|:.|||||||||..||||||.|.:...|.|||||.:|.|:|..:|:.||:.|.:|||:|..|
plant   437 FESFKTNSFEQFCINLTNEKLQQHFNQHVFKMEQDEYNKEEIDWSYIEFVDNQEILDLIEKKAGG 501

  Fly   477 IISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYS 541
            |||:|:|.|:.| ..|.:||.||:.|....|.|:         .|..:.|.:|.:.||||:|||.
plant   502 IISLLNEACMFP-RATHETFAEKMYQTFKDHKHF---------SKPKLSRTDFTICHYAGDVTYQ 556

  Fly   542 VNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFP--EKELRSLKRPETAITQFRASLNNLMDILMC 604
            ...||:||.|.:..:.:..|:.:....|.:.||  .::.....:..:..::|:..|..|::.|..
plant   557 TEQFLEKNKDYVVAEHQTLLNASRCAFVASLFPLLAEDANKKSKFSSISSRFKQQLVTLLETLST 621

  Fly   605 KEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERY-----KS 664
            .||.||||:|||:|....:|.::.||.|::..|:||.:|:..|||..|:.:|.||||:     :.
plant   622 TEPHYIRCVKPNNLLKPLIFENQNVLQQLRCGGVMEAIRISCAGFPTRKKFEEFLERFSVLAPEV 686

  Fly   665 LSKST--WPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIA 727
            |.|||  ||.   ........::|::.:..  :.|::|:||:|:| ...:.|.:....|.....|
plant   687 LDKSTDGWPL---SSTDDVACKKLLEKVAL--QGYQIGKTKVFLR-AGQMADLDARRNEVLGRAA 745

  Fly   728 AIIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRK-------------------------LAQQAAK 767
            :.||..::..:.|:.:|.||.....||:.||.:                         ||:::.|
plant   746 SRIQRKFRSYLSRKTFLMLRKVATNMQAVCRGQLSRLIFEGLRRDAAVLEIQRDIRMHLARKSYK 810

  Fly   768 KRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTKVLDKSWPHAPGHCEEA 832
            :...||..|:..|:|..:|.                  .||..::      ||:......||.:.
plant   811 ELYFAAVSIQLGIRGMASRG------------------RLRFQRQ------DKAAIMIQSHCRKF 851

  Fly   833 SGILHRLHRLHLARI-----YRLKLTPQQKRQFELKVLAEKVFKGKKNNYASSVS--TW-FQ-ED 888
            ...|| ..||..|.|     :|.:|..::.|:.::......|.:..|:.....|.  || .| |.
plant   852 LAQLH-YQRLKKAAITTQSAWRARLARKELRKLKMAAKETGVLEAAKSKLEKQVEELTWKLQLEK 915

  Fly   889 RI---PKEHIQRVNDFVASTFGSEQLKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQK 950
            |:   .:|...:.|..:.|.....||:::                    ..||:::.:.:..|:.
plant   916 RMRTDMEESKTQENAKLRSALEEMQLQFK--------------------ETKALHLQEVEAAKKM 960

  Fly   951 -------HRLPLDKIDFT--LTNHNDDLMVIRIPLDLKKDKGDLIL---------IIPRIIEFST 997
                   ..:|:...:..  ||:.|:.|..:...||.|.|:.:...         .:.:.||..|
plant   961 AETVPVLQEVPVVDTELVEKLTSENEKLKSLVSSLDQKIDETEKKFEERSKINEERLKQAIEAET 1025

  Fly   998 YIIDTVGTASIVSIVDRNSLEHNVVKGKGGVIDIQTGAEPGVVRDK------GHL 1046
                        :||:..:..|.:   :..::|::  :|..::|.|      |||
plant  1026 ------------TIVNLKTAVHEL---QEKILDVE--SENKILRQKSLIQASGHL 1063

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc	32..720	CDD:214580	280/706 (40%)
		MYSc_Myo1	52..707	CDD:276829	271/674 (40%)
		Myosin_TH1	863..1035	CDD:283635	32/196 (16%)
XIH	NP_194600.2	Myosin_N	12..47	CDD:280832
		MYSc	56..738	CDD:214580	280/706 (40%)
		MYSc_Myo11	75..726	CDD:276835	271/674 (40%)
		Apolipoprotein	893..1041	CDD:279749	30/182 (16%)
		DUF4355	893..1011	CDD:290964	24/137 (18%)
		Ax_dynein_light	<978..1023	CDD:287215	9/44 (20%)
		MyosinXI_CBD	1109..1486	CDD:271259
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910