Protein Alignment Myo61F and VIIIB

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001328307.1
• Gene: VIIIB / 828845
• AraportID: AT4G27370
• Length: 1136
• Species: Arabidopsis thaliana
• Alignment Length: 936
• Identity: 316/936 - (33%)
• Similarity: 493/936 - (52%)
• Gaps: 110/936 - (11%)

  Fly    38 GVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYE 102
            ||:|...| :|.:|.:.:.||:.|:.:||||:..|.|||:|||:|.:.||.::.:.||: |:..:
plant   167 GVEDLTQL-SYLNEPSLLYNLRVRYSQDLIYSKAGPVLIAVNPFKNVQIYGEEFLSAYQ-KNALD 229

  Fly   103 MPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLK 167
             .||::||.|.|:..::.|.:.|.::||||||:||||.:|..:|::.|..|...   ||::::||
plant   230 -APHVYAVADAAYDDMMREEKNQSIIISGESGAGKTETAKYAMQYLEALGGGSF---GVENEILK 290

  Fly   168 SNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFY 232
            :|.:|||||||||:||||||||||.|:|.|..||...|..:..:.|::|||.....|||.:||||
plant   291 TNCILEAFGNAKTSRNDNSSRFGKLMEIHFSAKGKICGAKLETFSLDQSRVAQLCNGERCYHIFY 355

  Fly   233 QLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFG 297
            ||.|||...|.:.|:: :|...|:||......|:.|.:||..|.::.:|..::...:|.|...|.
plant   356 QLCAGASPILKERLKI-KAASEYNYLNQSNCLTIDRTDDAQKFHKLMEAFNIVQIPQEYQERTFA 419

  Fly   298 IVASILHLGNVGFTEV--EGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLN 360
            ::|::|.||||.|..:  |.:.:|.:.:.|...|.|:|.|:.:|...|:...:.|..|.:...|.
plant   420 LLAAVLWLGNVSFEVIDNENHVEVVADEAVTNVAMLMGCNSKKLMVVLSTCKLQAGRDCIAKRLT 484

  Fly   361 QELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCI 425
            ...|...||:|||.:|..||:|||:::||||:...:|..|:  :.||||||||.|:.||||||||
plant   485 LRQATDMRDSLAKIIYASLFNWLVEQINISLEVGNSRTGRS--ISILDIYGFESFKDNSFEQFCI 547

  Fly   426 NFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGIISILDEECLRPGE 490
            |:.||:|||.|.....|.||:||..:||:|..||:.||:...||||:|..|::|:|:||...| :
plant   548 NYANERLQQHFNRHLFKLEQEEYEGDGIDWTKVEFIDNQECLNLIEKKPIGLVSLLNEESNFP-K 611

  Fly   491 PTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFR 555
            .||.||..||.|          |..|.:..|....|. ||:.||||||.|:.||||:||.|.|..
plant   612 ATDTTFANKLKQ----------HLNANSCFKGERGRG-FRIKHYAGEVLYNTNGFLEKNRDPLHV 665

  Fly   556 DLKETLSKAGNGIVRNCFPEKELRSLKRPET--------AITQFRASLNNLMDILMCKEPSYIRC 612
            ||.:.||.....:: |.|..|......:|.|        .|.:|:..|..||:.|....|.:|||
plant   666 DLIQLLSLCKCQLL-NLFSTKMHHDFLKPATFSDSMNQSVIAKFKGQLFKLMNKLEDTTPHFIRC 729

  Fly   613 IKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPG 677
            ||||..|...::.:..||.|::..|::|.:|:.|:|:..|.|::....||..|...|    :...
plant   730 IKPNSNQLPGLYEENHVLQQLRCCGVLEIVRISRSGYPTRLTHQELAVRYGCLLLDT----RISQ 790

  Fly   678 GPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAI--IQAHWKGLMQR 740
            .|.:..:.::|......|.|:||.||:::| ...:...|   :.||:.:..|  :|..::|...|
plant   791 DPLSTSKAILKQCNLPPEMYQVGYTKIYLR-TGVISVLE---ERKKYVLRGILGLQKQFRGYQTR 851

  Fly   741 RKYLKLRAQVIIMQSYCRRKLAQQ-------------AAKKRREAADKIRAFIKGFITR------ 786
            ..:..:|...:|:|||.|.:.|::             |..|..:||..::..::.::.|
plant   852 EYFHNMRNAAVILQSYIRGENARRNYIVVGESAIVSTAITKELDAAIHLQYMVRKWLARKLLNST 916

  Fly   787 --NDAPNGFNEEFIANAKRMWLLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYR 849
              .:.|.  ||:  ...:|....|::::  .::|.:.:...|  |     :|..|.    :|:.:
plant   917 QQKNKPR--NEK--KKTRRKSTKRVSED--KELLSEQFEVQP--C-----VLADLQ----SRVLK 964

  Fly   850 LKLTPQQKR------QFELKVLAEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGS 908
            ::....||.      |.||:...|:..: .:....|...||       ::|:           .|
plant   965 VEAAIMQKEDENTALQEELQRFEERWLE-NETRMKSMEDTW-------QKHM-----------SS 1010

  Fly   909 EQLKYQSFC-----TKFDRHGYKSRD 929
            .|:...:.|     .|...||..|.|
plant  1011 MQMSLAAACKVLAPDKTASHGTDSED 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	261/664 (39%)
		Myosin_TH1	863..1049	CDD:461801	13/72 (18%)
VIIIB	NP_001328307.1	MYSc_Myo8	180..820	CDD:276834	261/664 (39%)