DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myo61F and XIF

DIOPT Version :9

Sequence 1:	NP_476934.2	Gene:	Myo61F / 38153	FlyBaseID:	FBgn0010246	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001323600.1	Gene:	XIF / 817748	AraportID:	AT2G31900	Length:	1557	Species:	Arabidopsis thaliana

Alignment Length:	1049	Identity:	345/1049 - (32%)
Similarity:	526/1049 - (50%)	Gaps:	152/1049 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLP-IYTDDHVKAYR 96
            |...|||.|...|. |..|...:.||..||..:.||||.|.:||:|||:::|| :|:...::.|:
plant    58 EAPPAGVDDMTKLA-YLHEPGVLHNLDCRFALNEIYTYTGNILIAVNPFQRLPHLYSVHMMEQYK 121

  Fly    97 NKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEG- 160
            ...|.|:.||:|||.|.::|::|.|.|.|.:|:|||||:||||.:|.:::::|...|...| ||
plant   122 GAAFGELSPHLFAVADTSYRAMINEARSQSILVSGESGAGKTETTKMLMRYLAFMGGRSDT-EGR 185

  Fly   161 -VKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGG 224
             |:.::|:|||||||||||||.:|:|||||||:::||||.:|...|..|..||||:|||......
plant   186 SVEQQVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDKRGKISGAAIRTYLLERSRVCQVSDP 250

  Fly   225 ERNFHIFYQLLAGADEALLQELRLERALD--TYSYLTDGLNGTVTRINDADSFKQVQQALTVIDF 287
            |||:|.||.|.|...|    |.:..:..|  |:.||.......|:.::||..:.:.:.|:.::..
plant   251 ERNYHCFYMLCAAPPE----EAKKFKVGDPRTFHYLNQTNCYEVSNVDDAREYLETRNAMDIVGI 311

  Fly   288 TKEEQREIFGIVASILHLGNVGFTEVE--GNAKV---NSRDLVVTAARLLGVNASELEAALTHRT 347
            .:|.|..||.:||:|||||||.|.:.|  .::|:   .||..:.|||.||..|...:|.:|..|.
plant   312 GQEAQDAIFRVVAAILHLGNVNFIKGEEADSSKLRDDKSRYHLQTAAELLMCNEKMMEDSLCKRV 376

  Fly   348 IDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISL-QAKETRASRNNVMGILDIYG 411
            |......:|.||:.|.|...||||||.||.|||.|:|.::|.|: |..:.:    :::|:|||||
plant   377 IVTPDGNITKPLDPESAASNRDALAKTVYSRLFDWIVDKINSSIGQDPDAK----SLIGVLDIYG 437

  Fly   412 FEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKG 476
            ||.|:.|||||.|||..||||||.|.:...|.||:||.||.|.|..||:.||:.:.:|||:|..|
plant   438 FESFKINSFEQLCINLTNEKLQQHFNQHVFKMEQEEYTREEINWSYVEFVDNQDVLDLIEKKPGG 502

  Fly   477 IISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYS 541
            ||::|||.|:.| :.|.:||.:|:.|....|..:         .|..:.:..|.:.||||:||||
plant   503 IIALLDEACMFP-KSTHETFAQKMYQTYKGHKRF---------SKPKLAQTAFTVNHYAGDVTYS 557

  Fly   542 VNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLKRPETAI---------TQFRASLNN 597
            ...|||||.|.:..:.:..|..:....|.|.||       ..||.|.         |:|:..|..
plant   558 AEQFLDKNKDYVVAEHQALLDASKCSFVANLFP-------PLPEDASKQSKFSSIGTRFKQQLQA 615

  Fly   598 LMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERY 662
            ||:.|...||.||||:|||.:....:|.::.||:|::..|::|.:|:..||:..:|.::.||:|:
plant   616 LMETLNTTEPHYIRCVKPNAVLKPGIFENDNVLNQLRCGGVLEAIRISCAGYPTKRAFDEFLDRF 680

  Fly   663 KSLSKSTWPNYKGPGG--PKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHE 725
            ..|:...      |.|  .|:....:...:|.  :.|::|:||:|:|..:..     ....::.|
plant   681 VMLATDV------PEGSDEKSACASICNKMGL--KGYQIGKTKIFLRAGQMA-----ELDARRTE 732

  Fly   726 IAA----IIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRKLAQQAAKK-RREAAD-----KIRA-- 778
            :.|    :||...:..:.|:::|..:...|.||...|.|||::..:. |||||.     .|||
plant   733 VLAGATKLIQRQIRTYLTRKEFLGQKRATIYMQKLWRAKLARKLYQNMRREAASICIQKNIRAHR 797

  Fly   779 ----FIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTK---VLDKSWPHAPGHCEEASGIL 836
                :.|...:......|.......|..|       ....||   ::.:.|.....|  ||
plant   798 ARKNYTKLQASATVIQTGLRTMSARNKHR-------HRRRTKAAIIIQREWRRHQVH--EA---- 849

  Fly   837 HRLHR---LHLARIYRLKLTPQQKRQFELKVLAEKVFKGKKNNYASSVS--TWFQEDRIPKEHIQ 896
            ::.|:   |.|..::|.|:..::.:...:........|..|:.....|.  ||    |:..|..|
plant   850 YKKHKKATLALQCLWRAKVARKELKNLRMAARETGALKEAKDKLEKRVEELTW----RLELEKNQ 910

  Fly   897 RVNDFVASTFGSEQLKYQSFCTKFDRHGYKSRDRFILLSNK-----AIYVLDGKTYKQKHRLPLD 956
            :.:        .|..|.|...        |.::....|..|     |..:.|    |:..:|.::
plant   911 KAD--------LEDAKAQEIA--------KLQNNLTELQEKLDEAYAAIIRD----KEAAKLAIE 955

  Fly   957 K----------IDFT----LTNHNDDLMVIRIPLDLKKDKGDLILIIPRIIEFSTYIIDTVGTAS 1007
            :          :|.|    |.:.|::|.|     ::.|.||.:     :..|...:.::....||
plant   956 QAPPIIKEVPVVDNTQLELLNSQNNELEV-----EVAKLKGKI-----KEFEVKCFALENDSRAS 1010

  Fly  1008 IVSIVDRNS 1016
            :....|..|
plant  1011 VTEAEDAKS 1019

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc	32..720	CDD:214580	277/708 (39%)
		MYSc_Myo1	52..707	CDD:276829	268/676 (40%)
		Myosin_TH1	863..1035	CDD:283635	32/175 (18%)
XIF	NP_001323600.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910