Protein Alignment Myo61F and myo1ca

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001418059.2
• Gene: myo1ca / 567536
• ZFINID: ZDB-GENE-070705-190
• Length: 1045
• Species: Danio rerio
• Alignment Length: 1041
• Identity: 540/1041 - (51%)
• Similarity: 717/1041 - (68%)
• Gaps: 32/1041 - (3%)

  Fly    24 QLKMETGLHERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYT 88
            :|.||:.|..|||.|||||:||||:.||.|||.||::|::|.|||||||.||:||||||:|.||:
Zfish    15 RLMMESALSARDRVGVQDFLLLENHNSEAAFIENLRRRYREGLIYTYIGSVLVSVNPYKELEIYS 79

  Fly    89 DDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSG 153
            ..:::.:|..:|||:.|||||:.||::|:|..|.|.||:|||||||:||||||||:||:......
Zfish    80 KQNMERHRGVNFYEISPHIFALADNSYRALRTERRDQCILISGESGAGKTEASKKILQYYTHICP 144

  Fly   154 NQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRV 218
            .:.....::::||:|||||||||||||.|||||||||||||||||:|||||||:|||||||||||
Zfish   145 TRNNTHTIRERLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDYKGAPIGGHILNYLLEKSRV 209

  Fly   219 VAQMGGERNFHIFYQLLAGADEALLQELRLERA-LDTYSYLTDGLNGTVTRINDADSFKQVQQAL 282
            ..|..||||||||||||.|.::.||:.|.|::. ...|.||..|....|:.|:|.:.:|.|:.||
Zfish   210 AHQNHGERNFHIFYQLLEGGEDLLLKRLGLDKTNPQHYHYLIKGNCPRVSSISDKNGWKVVRNAL 274

  Fly   283 TVIDFTKEEQREIFGIVASILHLGNVGFTE-VEGNAKVNSRDLVVTAARLLGVNASELEAALTHR 346
            |:|.|..||.:.:..||||:|||||..|.| .||...:.:...:...::||||:.|.|:|||||:
Zfish   275 TIIGFEDEEIQALMEIVASVLHLGNTQFGEDEEGETHITTEAQLQFLSQLLGVDGSVLKAALTHK 339

  Fly   347 TIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKET---RASRNNVMGILD 408
            .|.|:|:.:.|||:.|.|:.|||:.|||:|.|.|:||||:||.||..|:.   .:..::|:|:||
Zfish   340 KIVAKGEEMISPLSLEQALSARDSFAKAIYGRAFTWLVQKLNQSLAFKDEIYYSSKCSSVIGLLD 404

  Fly   409 IYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEK 473
            |||||:||.|||||||||:||||||||||||||||||:||..||:.|..||||:||:||:|:|||
Zfish   405 IYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGVVWERVEYFNNKIICDLVEEK 469

  Fly   474 HKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEV 538
            |||||:||||||||.|:.:|.||||||...|..|.|::.|:.|...|:|.:.|:|||||||||||
Zfish   470 HKGIIAILDEECLRRGDASDITFLEKLEDTLGGHAHFITHKMANGKIRKAIGREEFRLVHYAGEV 534

  Fly   539 TYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLKRPETAITQFRASLNNLMDILM 603
            .|:||||||||||||:|.|||.|.::.|.||..||...||...:|||||.|||:.||..||||||
Zfish   535 NYNVNGFLDKNNDLLYRHLKEVLCQSTNHIVSQCFHADELMDQRRPETAATQFKLSLAKLMDILM 599

  Fly   604 CKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKS 668
            .|||||:|||||||.:....|::.||.|||||||||||||||||||||||:||.||||||||...
Zfish   600 SKEPSYVRCIKPNDGKQPGRFDEVLVRHQVKYLGLMENLRVRRAGFAYRRSYEAFLERYKSLCPD 664

  Fly   669 TWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAH 733
            ||||:.  |....||..|||.|.:..|::::|.:|:|||:|||||.||||.:.:|..||..:|..
Zfish   665 TWPNWH--GNLPEGVATLVKHLNYKPEEFKLGRSKIFIRFPRTLFITEDALEAQKQTIAVTLQKS 727

  Fly   734 WKGLMQRRKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFI 798
            |:|..:|..|.::|..||::||:.|....::.||.||:|||.||.||||||.||:.....||.|:
Zfish   728 WRGYRERANYHRIRHAVIVIQSWWRGVKGRRKAKHRRQAADTIRNFIKGFILRNEPRCPDNEYFL 792

  Fly   799 ANAKRMWLLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELK 863
            .:.:..:|:::.:.||..|||||||..|....|||..:||:...:|...|..::.|:.::|.|.|
Zfish   793 DHVRFSFLMKVKRNLPKSVLDKSWPKPPPSLTEASEHIHRICIRNLVNDYCRRIQPEWRKQLEQK 857

  Fly   864 VLAEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGSE-QLKYQSFCTKFDRHGYKS 927
            |:|..:|||:|:.|:.||...|...|:..|.|   |..|..|.||: ::||....||:||||::.
Zfish   858 VVASGIFKGQKDGYSRSVPKLFVATRLEAEEI---NLKVLQTLGSDNKVKYGIAVTKYDRHGFRP 919

  Fly   928 RDRFILLSNKAIYVLDGKTYKQKHRLPLDKIDF------TLTNHNDDLMVIRIPLDLKKDKGDLI 986
            |.|.:||:..:..::.....||       :||:      ::::.:|...|:.||....|.||||:
Zfish   920 RVRQLLLTTSSAVLVQEAKIKQ-------RIDYGALLGISVSSLSDGFFVLHIPTADSKQKGDLV 977

  Fly   987 LIIPRIIEFST---YIIDTVGTASIVSIVDRNSLEHNVVKGKGGVIDIQTGAEPGVVRDK-GHLV 1047
            |....:||..|   .:.|.:...:|    .::|:...:.:||.||||..:|::..||:.| |||.
Zfish   978 LQCDHVIEAVTKLAIMADKIHNVNI----SQDSIRFAIARGKEGVIDFTSGSDLRVVKSKNGHLS 1038

  Fly  1048 I 1048
            :
Zfish  1039 V 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	392/659 (59%)
		Myosin_TH1	863..1049	CDD:461801	64/197 (32%)
myo1ca	NP_001418059.2	None