Protein Alignment Myo61F and myo1f

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001243600.1
• Gene: myo1f / 565345
• ZFINID: ZDB-GENE-081104-506
• Length: 1095
• Species: Danio rerio
• Alignment Length: 1046
• Identity: 383/1046 - (36%)
• Similarity: 551/1046 - (52%)
• Gaps: 180/1046 - (17%)

  Fly    36 RAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHF 100
            ::||.|.|||... :|:|.:.||||||.:|.|:||||.|||||||:||:|.:||..::.|:....
Zfish    14 QSGVDDMVLLSKI-TEDAIVENLKKRFLDDYIFTYIGPVLISVNPFKQMPYFTDREIELYQGAAQ 77

  Fly   101 YEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKL 165
            ||.||||:|:|||.:|:::.::..|||:||||||:|||.|:|.::.:|:..||..:.|:.|||.:
Zfish    78 YENPPHIYALTDNMYRNMMIDSENQCVIISGESGAGKTVAAKYIMGYISKVSGGGSKVQHVKDII 142

  Fly   166 LKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHI 230
            |:|||:|||||||||.||:||||||||.:|||...|.|.||.|.|:||||||||:|...||||||
Zfish   143 LQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNENERNFHI 207

  Fly   231 FYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREI 295
            ||||:.|......:.|.: ...|.|.||.......|...||:..|::..:|:.||...:..|...
Zfish   208 FYQLIDGCTPQQKEGLGI-MTPDYYYYLNQSGTYKVDGTNDSKDFQETMEAMQVIGIPEMHQTLA 271

  Fly   296 FGIVASILHLGNVGFTEVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDA----RGDVVT 356
            ..|||.|||||::.|.||....:|.|.||:...|.|||::.:.|:..||.|.:|:    :.:.:.
Zfish   272 LQIVAGILHLGSINFIEVGNYGQVESTDLLAFPAYLLGIDQNRLQEKLTSRIMDSKWAGKTESIN 336

  Fly   357 SPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFE 421
            ..||.|.|.:.|||||||:|.|||.:||:.:|.::|......|    :|:||||||||||:|.||
Zfish   337 VTLNLEQARHTRDALAKALYTRLFDYLVEEINKAMQKPIEELS----VGVLDIYGFEIFQRNGFE 397

  Fly   422 QFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEK--HKGIISILDEE 484
            ||||||.||||||:|||||||:||:||.:|||:|.|:|||:||::|:|||.|  ..||:|:||:.
Zfish   398 QFCINFVNEKLQQIFIELTLKAEQEEYVQEGIKWTPIEYFNNKIVCDLIENKLSPPGIMSVLDDV 462

  Fly   485 CL---RPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFL 546
            |.   ...:..|.|.|:||...:..|.|:......            |.:.||||:|:|.:|||.
Zfish   463 CATMHATKDGADMTLLQKLQNAVGTHDHFNSWNSG------------FIIHHYAGKVSYDINGFC 515

  Fly   547 DKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLK-RPETAITQFRASLNNLMDILMCKEPSYI 610
            ::|.|:||.||.|.:..:....:::.|||......| ||.||.::.:...|.|:..||...|.||
Zfish   516 ERNRDVLFPDLIELMQSSQYDFIQSLFPENLNTDKKGRPTTAGSKIKRQANELVSTLMKCTPHYI 580

  Fly   611 RCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKG 675
            ||||||:.:....:.:....|||:||||.||:|||||||||||.:..||.||..|:..|||.::
Zfish   581 RCIKPNETKRPKDWEESRARHQVEYLGLRENIRVRRAGFAYRRIFPKFLHRYAILTAETWPCWR- 644

  Fly   676 PGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQR 740
             |..:.||..|::.:..:.::|::|.:|:||:.|.:||..|:..:.|....|..||..|:..:.|
Zfish   645 -GAEQQGVLHLLRTVNMETDQYQMGRSKIFIKNPESLFLLEEMRERKFDTFARTIQKAWRKYIAR 708

  Fly   741 RKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMW 805
            |||.::|
Zfish   709 RKYEQMR---------------------------------------------------------- 715

  Fly   806 LLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVF 870
                                    ||||.||:
Zfish   716 ------------------------EEASDILY--------------------------------- 723

  Fly   871 KGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGSEQLKYQSFCTKFDRHGYKSRDRFILLS 935
             ..|....:|::..|..|.:..|....:..|:|.   .|::.:.....||||. :||..|.::||
Zfish   724 -NSKERRRNSINRNFVGDYLGMEDRPELRQFMAK---RERVDFADSVNKFDRR-FKSIKRDLILS 783

  Fly   936 NKAIYVLDGKTYKQ-----------KHRLPLDKI-DFTLTNHNDDLMVIRIPLDLKKDKGDLILI 988
            .|:||::..:..|:           |.||.:..| ..:|:...||..:      |.:.:.|.:|.
Zfish   784 PKSIYLIGREKIKKGPEKGQIKEVLKRRLDISGIRSVSLSTRQDDFFI------LHETEYDSLLE 842

  Fly   989 IPRIIEFSTYII----DTVGTASIVSIVDRNSLEHNVVK-GKGG----VIDIQTG-AEPGVVRDK 1043
            .....||.|.:.    :...:...:|..||  |:.||.| |.||    ::..|.| |:..|::..
Zfish   843 SMFKTEFLTLLCKRYEEQTRSKLTLSFSDR--LQFNVKKEGWGGGSTRMVVFQRGQADEAVIKAG 905

  Fly  1044 GHLVII 1049
            |..:.:
Zfish   906 GKTLTV 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	306/664 (46%)
		Myosin_TH1	863..1049	CDD:461801	49/207 (24%)
myo1f	NP_001243600.1	MYSc_Myo1	29..675	CDD:276829	306/664 (46%)
		Myosin_TH1	715..913	CDD:461801	56/325 (17%)
		SH3_MyoIe_If_like	1042..1094	CDD:212761